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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	beta-Narcotine
Molecular formula	C22H23NO7
IUPAC name	(3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one
Molecular weight	413.426
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	2.7
Synonyms	(3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one AKOS021650200 CHEBI:93592 KBio2_004117 Longactin NCGC00015757-03 Noscapinum [INN-Latin] Spectrum4_000456 3860-46-6 BRN 0099933 Coscopin (VAN) KBioGR_000872 MCULE-4671292218 NCGC00016388-03 SCHEMBL7862895 ST055757 (-)-alpha-Norcotine AB00053507_10 CAS-128-62-1 HSDB 3372 L-alpha-Noscapine NCGC00015757-01 Noscapina [INN-Spanish] Spectrum2_000987 ZINC19418976 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R-(R,R))- KBio2_006685 Lopac-N-9007 NCGC00015757-06 Noskapin Spectrum5_001276 5-(6,7-Dimethoxyphthalidyl)-5,6,7,8-tetrahydro-4-methoxy-8-methyl-1,3-dioxolo(4,5-g)isoquinoline BSPBio_002113 DTXSID70191919 KBioSS_001549 MolPort-000-720-123 NCGC00017174-01 SDCCGMLS-0066644.P001 TNP00034 (3R)-3-((5R)-4-methoxy-6-methyl(5,6,7,8-tetrahydro-2H-1,3-dioxoleno[4,5-g]isoq uinolin-5-yl))-6,7-dimethoxy-3-hydroisobenzofuran-1-one AC1L1LK8 CCG-36462 KBio2_001549 L-beta-Narcotine NCGC00015757-02 Noscapine [INN:BAN:JAN] Spectrum3_000527 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (S-(R,S))- BRD-K91301684-003-02-2 CHEMBL1403892 KBio3_001613 LS-97535 NCGC00016388-01 SBI-0206692.P002 Spectrum_001069 (-)-3-(2-Methyl-6,7-methylendioxy-8-methoxy-1-isochinolyl)-6,7-dimethoxyphthalid 8-Methoxyhydrastin C22H23NO7 EINECS 204-899-2 L-alpha-2-Methyl-8-methoxy-6,7-methylenedioxy-1-(6,7-dimethoxy-3-phthalidyl)-1,2,3,4-tetrahydroisoquinaline NARCOTINE NCGC00017174-02 SPBio_001053 TNP00110 [ Show all ]
Inchi Key	AKNNEGZIBPJZJG-QZTJIDSGSA-N
Inchi ID	InChI=1S/C22H23NO7/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18/h5-6,9,17-18H,7-8,10H2,1-4H3/t17-,18-/m1/s1
PubChem CID	31411
ChEMBL	CHEMBL1403892
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7719	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460

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