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Ligand

NameCHEMBL194206
Molecular formulaC23H30FN5O2
IUPAC name4-(4-fluorophenyl)-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]piperazine-1-carboxamide
Molecular weight427.524
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogP2.7
Synonyms4-(4-Fluoro-phenyl)-piperazine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
BDBM50173090
Inchi KeyAOENLUNXEDMDRT-UHFFFAOYSA-N
Inchi IDInChI=1S/C23H30FN5O2/c1-26-9-11-28(12-10-26)21-17-19(5-8-22(21)31-2)25-23(30)29-15-13-27(14-16-29)20-6-3-18(24)4-7-20/h3-8,17H,9-16H2,1-2H3,(H,25,30)
PubChem CID44403098
ChEMBLCHEMBL194206
IUPHARN/A
BindingDB50173090
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 21
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
101735-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
101835-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
101785-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
101765-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
101865-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
101695-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
101875-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
10171D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
10175D(1B) dopamine receptorP21918DRD5Homo sapiens (Human)477
10168D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
10170D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
10182D(4) dopamine receptorP21917DRD4Homo sapiens (Human)467
10188Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
10180Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
10185Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380
10174Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400
10177Muscarinic acetylcholine receptor M1P11229CHRM1Homo sapiens (Human)460
10184Muscarinic acetylcholine receptor M2P08172CHRM2Homo sapiens (Human)466
10181Muscarinic acetylcholine receptor M3P20309CHRM3Homo sapiens (Human)590
10172Muscarinic acetylcholine receptor M4P08173CHRM4Homo sapiens (Human)479

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