SEQ2FUN

BioLiP
Download all results in tab-seperated text for 1072681 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    252201 4nod:A (2.897) BS02 dna ? N/A Q00059 24435062
    252202 4nod:A (2.897) BS03 dna ? N/A Q00059 24435062
    252203 4nod:B (2.897) BS01 dna ? N/A Q00059 24435062
    252204 4nod:B (2.897) BS02 dna ? N/A Q00059 24435062
    252205 4nod:B (2.897) BS03 dna ? N/A Q00059 24435062
    252206 4nod:G (2.897) BS01 dna ? N/A Q00059 24435062
    252207 4nod:G (2.897) BS02 dna ? N/A Q00059 24435062
    252208 4nod:H (2.897) BS01 dna ? N/A Q00059 24435062
    252209 4nod:H (2.897) BS02 dna ? N/A Q00059 24435062
    252210 4noe:A (2.2) BS01 dna ? N/A Q9RY80 27044084
    252211 4noe:B (2.2) BS01 dna ? N/A Q9RY80 27044084
    252212 4noe:C (2.2) BS01 dna ? N/A Q9RY80 27044084
    252213 4noe:D (2.2) BS01 dna ? N/A Q9RY80 27044084
    252214 4noe:E (2.2) BS01 dna ? N/A Q9RY80 27044084
    252215 4nog:A (1.2) BS01 PLP 2.6.1.13 GO:0004587 ... S8EY38 30345257
    252216 4nog:B (1.2) BS01 PLP 2.6.1.13 GO:0004587 ... S8EY38 30345257
    252217 4non:A (2.5) BS01 GDP ? GO:0005525 ... Q5M586 24649829 MOAD: Kd=5.71uM
    252218 4non:B (2.5) BS01 GDP ? GO:0005525 ... Q5M586 24649829 MOAD: Kd=5.71uM
    252219 4nos:A (2.25) BS01 ZN 1.14.13.39 GO:0004517 ... P35228 10074942
    252220 4nos:A (2.25) BS02 HEM 1.14.13.39 GO:0004517 ... P35228 10074942
    252221 4nos:A (2.25) BS03 H2B 1.14.13.39 GO:0004517 ... P35228 10074942
    252222 4nos:A (2.25) BS04 ITU 1.14.13.39 GO:0004517 ... P35228 10074942 MOAD: Ki=19nM
    BindingDB: IC50=160nM
    252223 4nos:A (2.25) BS05 H4B 1.14.13.39 GO:0004517 ... P35228 10074942
    252224 4nos:B (2.25) BS01 ZN 1.14.13.39 GO:0004517 ... P35228 10074942
    252225 4nos:B (2.25) BS02 H2B 1.14.13.39 GO:0004517 ... P35228 10074942
    252226 4nos:B (2.25) BS03 HEM 1.14.13.39 GO:0004517 ... P35228 10074942
    252227 4nos:B (2.25) BS04 H4B 1.14.13.39 GO:0004517 ... P35228 10074942
    252228 4nos:B (2.25) BS05 ITU 1.14.13.39 GO:0004517 ... P35228 10074942 MOAD: Ki=19nM
    BindingDB: IC50=160nM
    252229 4nos:C (2.25) BS01 ZN 1.14.13.39 GO:0004517 ... P35228 10074942
    252230 4nos:C (2.25) BS02 HEM 1.14.13.39 GO:0004517 ... P35228 10074942
    252231 4nos:C (2.25) BS03 H4B 1.14.13.39 GO:0004517 ... P35228 10074942
    252232 4nos:C (2.25) BS04 ITU 1.14.13.39 GO:0004517 ... P35228 10074942 MOAD: Ki=19nM
    BindingDB: IC50=160nM
    252233 4nos:C (2.25) BS05 H4B 1.14.13.39 GO:0004517 ... P35228 10074942
    252234 4nos:D (2.25) BS01 ZN 1.14.13.39 GO:0004517 ... P35228 10074942
    252235 4nos:D (2.25) BS02 H4B 1.14.13.39 GO:0004517 ... P35228 10074942
    252236 4nos:D (2.25) BS03 HEM 1.14.13.39 GO:0004517 ... P35228 10074942
    252237 4nos:D (2.25) BS04 H4B 1.14.13.39 GO:0004517 ... P35228 10074942
    252238 4nos:D (2.25) BS05 ITU 1.14.13.39 GO:0004517 ... P35228 10074942 MOAD: Ki=19nM
    BindingDB: IC50=160nM
    252239 4not:A (2.35) BS01 MN ? GO:0005509 ... B3EWJ2 N/A
    252240 4not:A (2.35) BS02 CA ? GO:0005509 ... B3EWJ2 N/A
    252241 4not:A (2.35) BS03 XMM ? GO:0005509 ... B3EWJ2 N/A
    252242 4np1:A (2.3) BS01 HEM ? GO:0005576 ... Q26239 N/A
    252243 4np1:B (2.3) BS01 HEM ? GO:0005576 ... Q26239 N/A
    252244 4np2:A (1.75) BS01 2L1 ? GO:0005540 ... P15379 24606063 MOAD: Kd=5.5mM
    BindingDB: Kd=5500000nM
    252245 4np3:A (1.61) BS01 2L2 ? GO:0005540 ... P15379 24606063 MOAD: Kd=0.5mM
    BindingDB: Kd=500000nM
    252246 4np5:A (1.5) BS01 CA 3.1.31.1 GO:0003676 ... P00644 N/A
    252247 4np5:A (1.5) BS02 THP 3.1.31.1 GO:0003676 ... P00644 N/A
    252248 4np7:A (1.99) BS01 FE2 3.1.8.1 GO:0008270 ... Q93LD7 24721933
    252249 4np7:A (1.99) BS02 CO 3.1.8.1 GO:0008270 ... Q93LD7 24721933
    252250 4np7:A (1.99) BS03 DPJ 3.1.8.1 GO:0008270 ... Q93LD7 24721933
    252251 4np9:A (1.92) BS01 I3P ? GO:0016020 ... P47709 24302762
    252252 4npb:A (2.147) BS01 GLC ? GO:0003756 ... A0A2S9PFA1 N/A
    252253 4npb:A (2.147) BS02 FRU ? GO:0003756 ... A0A2S9PFA1 N/A
    252254 4npi:A (1.94) BS01 NAD ? GO:0016491 ... Q83V33 25565451
    252255 4npi:A (1.94) BS02 2VS ? GO:0016491 ... Q83V33 25565451
    252256 4npi:B (1.94) BS01 NAD ? GO:0016491 ... Q83V33 25565451
    252257 4npi:B (1.94) BS02 2VS ? GO:0016491 ... Q83V33 25565451
    252258 4npi:C (1.94) BS01 NAD ? GO:0016491 ... Q83V33 25565451
    252259 4npi:C (1.94) BS02 2VS ? GO:0016491 ... Q83V33 25565451
    252260 4npi:D (1.94) BS01 NAD ? GO:0016491 ... Q83V33 25565451
    252261 4npi:D (1.94) BS02 2VS ? GO:0016491 ... Q83V33 25565451
    252262 4npk:A (2.552) BS01 CA ? GO:0006869 ... A0FGR8 24373768
    252263 4npk:A (2.552) BS02 CA ? GO:0006869 ... A0FGR8 24373768
    252264 4npk:A (2.552) BS03 CA ? GO:0006869 ... A0FGR8 24373768
    252265 4npl:A (1.651) BS01 MN 1.14.11.53 GO:0006397 ... Q08BA6 24561204
    252266 4npl:A (1.651) BS02 AKG 1.14.11.53 GO:0006397 ... Q08BA6 24561204
    252267 4npl:B (1.651) BS01 MN 1.14.11.53 GO:0006397 ... Q08BA6 24561204
    252268 4npl:B (1.651) BS02 AKG 1.14.11.53 GO:0006397 ... Q08BA6 24561204
    252269 4npm:A (1.803) BS01 MN 1.14.11.53 GO:0006397 ... Q08BA6 24561204
    252270 4npm:B (1.803) BS01 MN 1.14.11.53 GO:0006397 ... Q08BA6 24561204
    252271 4npt:A (1.66) BS01 017 ? GO:0004190 ... O38896 24738918
    252272 4npv:A (2.4) BS01 0NK 3.1.4.17 GO:0004114 ... Q01064 N/A BindingDB: IC50=35nM
    252273 4npv:A (2.4) BS02 ZN 3.1.4.17 GO:0004114 ... Q01064 N/A
    252274 4npw:A (1.9) BS01 ZN 3.1.4.17 GO:0004114 ... Q01064 N/A
    252275 4npw:A (1.9) BS02 0NY 3.1.4.17 GO:0004114 ... Q01064 N/A
    252276 4nq2:A (1.55) BS01 ZN 3.5.2.6 GO:0008800 ... Q9K2N0 25356958
    252277 4nq2:A (1.55) BS02 ZN 3.5.2.6 GO:0008800 ... Q9K2N0 25356958
    252278 4nq3:A (2.702) BS01 BR8 3.5.2.15 GO:0016812 ... A8IKD2 24915109
    252279 4nq3:A (2.702) BS02 MG 3.5.2.15 GO:0016812 ... A8IKD2 24915109
    252280 4nq3:B (2.702) BS01 BR8 3.5.2.15 GO:0016812 ... A8IKD2 24915109
    252281 4nq3:B (2.702) BS02 MG 3.5.2.15 GO:0016812 ... A8IKD2 24915109
    252282 4nq4:A (1.67) BS01 ZN 3.5.2.6 GO:0008270 ... P04190 N/A
    252283 4nq4:A (1.67) BS02 ZN 3.5.2.6 GO:0008270 ... P04190 N/A
    252284 4nq5:A (2.29) BS01 ZN 3.5.2.6 GO:0008270 ... P04190 N/A
    252285 4nq5:A (2.29) BS02 ZN 3.5.2.6 GO:0008270 ... P04190 N/A
    252286 4nq5:A (2.29) BS03 3C7 3.5.2.6 GO:0008270 ... P04190 N/A
    252287 4nq6:A (1.8) BS01 ZN 3.5.2.6 GO:0008270 ... P04190 27303030
    252288 4nq6:A (1.8) BS02 ZN 3.5.2.6 GO:0008270 ... P04190 27303030
    252289 4nq6:A (1.8) BS03 3R9 3.5.2.6 GO:0008270 ... P04190 27303030
    252290 4nq8:A (1.5) BS01 PAF ? GO:0030288 ... A0A0H3LPK2 25540822
    252291 4nq8:B (1.5) BS01 PAF ? GO:0030288 ... A0A0H3LPK2 25540822
    252292 4nqa:A (3.102) BS01 peptide ? GO:0003677 ... P19793 24561505
    252293 4nqa:A (3.102) BS02 dna ? GO:0003677 ... P19793 24561505
    252294 4nqa:A (3.102) BS03 dna ? GO:0003677 ... P19793 24561505
    252295 4nqa:A (3.102) BS04 9CR ? GO:0003677 ... P19793 24561505 BindingDB: EC50=100nM, Ki=583nM, IC50=32nM, Kd=240nM
    252296 4nqa:A (3.102) BS05 ZN ? GO:0003677 ... P19793 24561505
    252297 4nqa:A (3.102) BS06 ZN ? GO:0003677 ... P19793 24561505
    252298 4nqa:B (3.102) BS01 peptide ? GO:0003677 ... P55055 24561505
    252299 4nqa:B (3.102) BS02 dna ? GO:0003677 ... P55055 24561505
    252300 4nqa:B (3.102) BS03 dna ? GO:0003677 ... P55055 24561505
    252301 4nqa:B (3.102) BS04 965 ? GO:0003677 ... P55055 24561505 BindingDB: EC50=40.0nM, IC50=23nM, Ki=2.2nM
    252302 4nqa:B (3.102) BS05 ZN ? GO:0003677 ... P55055 24561505
    252303 4nqa:B (3.102) BS06 ZN ? GO:0003677 ... P55055 24561505
    252304 4nqa:H (3.102) BS01 peptide ? GO:0003677 ... P19793 24561505
    252305 4nqa:H (3.102) BS02 dna ? GO:0003677 ... P19793 24561505
    252306 4nqa:H (3.102) BS03 dna ? GO:0003677 ... P19793 24561505
    252307 4nqa:H (3.102) BS04 9CR ? GO:0003677 ... P19793 24561505 BindingDB: EC50=100nM, Ki=583nM, IC50=32nM, Kd=240nM
    252308 4nqa:H (3.102) BS05 ZN ? GO:0003677 ... P19793 24561505
    252309 4nqa:H (3.102) BS06 ZN ? GO:0003677 ... P19793 24561505
    252310 4nqa:I (3.102) BS01 peptide ? GO:0003677 ... P55055 24561505
    252311 4nqa:I (3.102) BS02 dna ? GO:0003677 ... P55055 24561505
    252312 4nqa:I (3.102) BS03 dna ? GO:0003677 ... P55055 24561505
    252313 4nqa:I (3.102) BS04 965 ? GO:0003677 ... P55055 24561505 BindingDB: EC50=40.0nM, IC50=23nM, Ki=2.2nM
    252314 4nqa:I (3.102) BS05 ZN ? GO:0003677 ... P55055 24561505
    252315 4nqc:A (2.5) BS01 2LJ ? N/A Q95460 24695216
    252316 4nqc:C (2.5) BS01 2LJ ? N/A Q95460 24695216
    252317 4nqd:A (2.2) BS01 2LJ ? N/A Q95460 24695216
    252318 4nqd:C (2.2) BS01 2LJ ? N/A Q95460 24695216
    252319 4nqe:A (2.1) BS01 2L4 ? N/A Q95460 24695216
    252320 4nqe:C (2.1) BS01 2L4 ? N/A Q95460 24695216
    252321 4nqg:A (1.301) BS01 CZH ? GO:0005509 ... P39047 N/A
    252322 4nqg:B (1.301) BS01 CZH ? GO:0005509 ... P39047 N/A
    252323 4nql:A (2.3) BS01 ZN 3.4.19.- GO:0008233 ... Q9P371 24787148
    252324 4nqm:A (1.58) BS01 Y1Z ? N/A O60885 N/A BindingDB: IC50=158nM
    252325 4nqn:A (1.73) BS01 Y1Z ? N/A Q9H8M2 N/A BindingDB: IC50=200nM
    252326 4nqq:A (3.2) BS01 CA ? GO:0005509 ... P10287 25253890
    252327 4nqq:A (3.2) BS02 CA ? GO:0005509 ... P10287 25253890
    252328 4nqq:A (3.2) BS03 CA ? GO:0005509 ... P10287 25253890
    252329 4nqq:B (3.2) BS01 CA ? GO:0005509 ... P10287 25253890
    252330 4nqq:B (3.2) BS02 CA ? GO:0005509 ... P10287 25253890
    252331 4nqq:B (3.2) BS03 CA ? GO:0005509 ... P10287 25253890
    252332 4nqq:C (3.2) BS01 CA ? GO:0005509 ... P10287 25253890
    252333 4nqq:C (3.2) BS02 CA ? GO:0005509 ... P10287 25253890
    252334 4nqq:C (3.2) BS03 CA ? GO:0005509 ... P10287 25253890
    252335 4nqq:D (3.2) BS01 CA ? GO:0005509 ... P10287 25253890
    252336 4nqq:D (3.2) BS02 CA ? GO:0005509 ... P10287 25253890
    252337 4nqq:D (3.2) BS03 CA ? GO:0005509 ... P10287 25253890
    252338 4nqr:A (1.09) BS01 ALA ? N/A Q3MFZ5 N/A
    252339 4nqr:A (1.09) BS02 MG ? N/A Q3MFZ5 N/A
    252340 4nqr:B (1.09) BS01 ALA ? N/A Q3MFZ5 N/A
    252341 4nqr:B (1.09) BS02 MG ? N/A Q3MFZ5 N/A
    252342 4nqv:A (2.39) BS01 peptide ? N/A P04439 24395804
    252343 4nqv:C (2.39) BS01 peptide ? N/A P04439 24395804
    252344 4nqv:E (2.39) BS01 peptide ? N/A P04439 24395804
    252345 4nqv:E (2.39) BS02 peptide ? N/A P04439 24395804
    252346 4nqv:G (2.39) BS01 peptide ? N/A P04439 24395804
    252347 4nqv:I (2.39) BS01 peptide ? N/A P04439 24395804
    252348 4nqv:K (2.39) BS01 peptide ? N/A P04439 24395804
    252349 4nqv:K (2.39) BS02 peptide ? N/A P04439 24395804
    252350 4nqx:A (2.0) BS01 peptide ? N/A P04439 24395804
    252351 4nqx:C (2.0) BS01 peptide ? N/A P04439 24395804
    252352 4nqx:E (2.0) BS01 peptide ? N/A P04439 24395804
    252353 4nqx:E (2.0) BS02 peptide ? N/A P04439 24395804
    252354 4nqx:G (2.0) BS01 peptide ? N/A P04439 24395804
    252355 4nqx:I (2.0) BS01 peptide ? N/A P04439 24395804
    252356 4nqx:K (2.0) BS01 peptide ? N/A P04439 24395804
    252357 4nqx:K (2.0) BS02 peptide ? N/A P04439 24395804
    252358 4nqy:A (2.6) BS01 ZN 4.2.1.31
    4.2.1.33
    4.2.1.35
    GO:0003861 ... P81291 24699638
    252359 4nqy:B (2.6) BS01 ZN 4.2.1.31
    4.2.1.33
    4.2.1.35
    GO:0003861 ... P81291 24699638
    252360 4nr0:A (1.799) BS01 NAD 1.3.1.9 GO:0004318 ... Q9ZFE4 N/A
    252361 4nr0:A (1.799) BS02 TCL 1.3.1.9 GO:0004318 ... Q9ZFE4 N/A
    252362 4nr0:B (1.799) BS01 NAD 1.3.1.9 GO:0004318 ... Q9ZFE4 N/A
    252363 4nr0:B (1.799) BS02 TCL 1.3.1.9 GO:0004318 ... Q9ZFE4 N/A
    252364 4nr0:C (1.799) BS01 NAD 1.3.1.9 GO:0004318 ... Q9ZFE4 N/A
    252365 4nr0:C (1.799) BS02 TCL 1.3.1.9 GO:0004318 ... Q9ZFE4 N/A
    252366 4nr0:D (1.799) BS01 NAD 1.3.1.9 GO:0004318 ... Q9ZFE4 N/A
    252367 4nr0:D (1.799) BS02 TCL 1.3.1.9 GO:0004318 ... Q9ZFE4 N/A
    252368 4nr1:A (2.68) BS01 peptide 1.14.11.30
    1.14.11.n4
    GO:0000122 ... Q9NWT6 N/A
    252369 4nr1:A (2.68) BS02 ZN 1.14.11.30
    1.14.11.n4
    GO:0000122 ... Q9NWT6 N/A
    252370 4nr4:A (1.69) BS01 2LK 2.3.1.-
    2.3.1.48
    N/A Q92793 N/A
    252371 4nr4:A (1.69) BS02 2LK 2.3.1.-
    2.3.1.48
    N/A Q92793 N/A
    252372 4nr4:B (1.69) BS01 2LK 2.3.1.-
    2.3.1.48
    N/A Q92793 N/A
    252373 4nr4:B (1.69) BS02 2LK 2.3.1.-
    2.3.1.48
    N/A Q92793 N/A
    252374 4nr5:A (1.66) BS01 2LL 2.3.1.-
    2.3.1.48
    N/A Q92793 N/A BindingDB: IC50=240nM
    252375 4nr6:A (1.66) BS01 2LN 2.3.1.-
    2.3.1.48
    N/A Q92793 N/A
    252376 4nr7:A (1.2) BS01 2LO 2.3.1.-
    2.3.1.48
    N/A Q92793 N/A BindingDB: Kd=21nM, IC50=2800nM, EC50=6900nM
    252377 4nr8:A (1.635) BS01 2LL ? N/A O60885 N/A BindingDB: IC50=4100nM
    252378 4nr9:A (1.98) BS01 ALY ? N/A Q9UIF8 24304323
    252379 4nra:A (1.85) BS01 2LW ? N/A Q9UIF8 24304323 MOAD: Kd=65uM
    BindingDB: IC50=37000nM, Kd=65000nM
    252380 4nrb:A (2.08) BS01 2LX ? N/A Q9UIF8 24304323 MOAD: ic50=38uM
    BindingDB: IC50=38000nM
    252381 4nrc:A (1.86) BS01 2LY ? N/A Q9UIF8 24304323 MOAD: ic50=241uM
    BindingDB: IC50=241000nM
    252382 4nre:A (2.63) BS01 FE2 1.13.11.-
    1.13.11.33
    GO:0005506 ... O15296 24497644
    252383 4nre:A (2.63) BS02 C8E 1.13.11.-
    1.13.11.33
    GO:0005506 ... O15296 24497644
    252384 4nre:A (2.63) BS03 C8E 1.13.11.-
    1.13.11.33
    GO:0005506 ... O15296 24497644
    252385 4nre:A (2.63) BS04 CA 1.13.11.-
    1.13.11.33
    GO:0005506 ... O15296 24497644
    252386 4nre:A (2.63) BS05 CA 1.13.11.-
    1.13.11.33
    GO:0005506 ... O15296 24497644
    252387 4nrk:A (2.63) BS01 SIA ? GO:0019031 ... P03460 24503069
    252388 4nrk:C (2.63) BS01 SIA ? GO:0019031 ... P03460 24503069
    252389 4nrk:E (2.63) BS01 GAL ? GO:0019031 ... P03460 24503069
    252390 4nrk:E (2.63) BS02 SIA ? GO:0019031 ... P03460 24503069
    252391 4nrl:A (2.72) BS01 SIA ? GO:0019031 ... P03460 24503069
    252392 4nrl:C (2.72) BS01 GAL ? GO:0019031 ... P03460 24503069
    252393 4nrl:C (2.72) BS02 SIA ? GO:0019031 ... P03460 24503069
    252394 4nrl:E (2.72) BS01 SIA ? GO:0019031 ... P03460 24503069
    252395 4nrn:A (1.802) BS01 ZN ? GO:0004521 ... O25552 24677509
    252396 4nrn:A (1.802) BS02 ZN ? GO:0004521 ... O25552 24677509
    252397 4nrn:B (1.802) BS01 ZN ? GO:0004521 ... O25552 24677509
    252398 4nrn:B (1.802) BS02 ZN ? GO:0004521 ... O25552 24677509
    252399 4nro:A (2.3) BS01 MN 1.14.11.53 GO:0006397 ... Q6P6C2 24616105
    252400 4nro:A (2.3) BS02 AKG 1.14.11.53 GO:0006397 ... Q6P6C2 24616105

    Reference:
  • Chengxin Zhang, Xi Zhang, Lydia Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).