SEQ2FUN

BioLiP
Download all results in tab-seperated text for 942758 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    370801 5l5x:Y (2.9) BS01 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370802 5l5x:Y (2.9) BS02 04C 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370803 5l5x:Z (2.9) BS01 MG 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370804 5l5x:b (2.9) BS01 04C 3.4.25.1 GO:0000502 ... P38624 27789522
    370805 5l5y:G (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370806 5l5y:H (2.7) BS01 3BV 3.4.25.1 GO:0004298 ... P25043 27789522
    370807 5l5y:H (2.7) BS02 3BV 3.4.25.1 GO:0004298 ... P25043 27789522
    370808 5l5y:I (2.7) BS01 3BV 3.4.25.1 GO:0000502 ... P25451 27789522
    370809 5l5y:I (2.7) BS02 MG 3.4.25.1 GO:0000502 ... P25451 27789522
    370810 5l5y:K (2.7) BS01 3BV 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370811 5l5y:K (2.7) BS02 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370812 5l5y:L (2.7) BS01 3BV 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370813 5l5y:N (2.7) BS01 3BV 3.4.25.1 GO:0000502 ... P38624 27789522
    370814 5l5y:N (2.7) BS02 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370815 5l5y:V (2.7) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    370816 5l5y:V (2.7) BS02 3BV 3.4.25.1 GO:0004298 ... P25043 27789522
    370817 5l5y:V (2.7) BS03 3BV 3.4.25.1 GO:0004298 ... P25043 27789522
    370818 5l5y:W (2.7) BS01 3BV 3.4.25.1 GO:0000502 ... P25451 27789522
    370819 5l5y:Y (2.7) BS01 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370820 5l5y:Y (2.7) BS02 3BV 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370821 5l5y:Z (2.7) BS01 3BV 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370822 5l5y:Z (2.7) BS02 MG 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370823 5l5y:b (2.7) BS01 3BV 3.4.25.1 GO:0000502 ... P38624 27789522
    370824 5l5y:b (2.7) BS02 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370825 5l5z:G (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370826 5l5z:H (2.7) BS01 BO2 3.4.25.1 GO:0004298 ... P25043 27789522
    370827 5l5z:I (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P25451 27789522
    370828 5l5z:K (2.7) BS01 BO2 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370829 5l5z:K (2.7) BS02 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370830 5l5z:N (2.7) BS01 BO2 3.4.25.1 GO:0000502 ... P38624 27789522
    370831 5l5z:N (2.7) BS02 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370832 5l5z:V (2.7) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    370833 5l5z:V (2.7) BS02 BO2 3.4.25.1 GO:0004298 ... P25043 27789522
    370834 5l5z:Y (2.7) BS01 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370835 5l5z:Y (2.7) BS02 BO2 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370836 5l5z:Z (2.7) BS01 MG 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370837 5l5z:b (2.7) BS01 BO2 3.4.25.1 GO:0000502 ... P38624 27789522
    370838 5l60:A (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P23639 27789522
    370839 5l60:G (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370840 5l60:I (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P25451 27789522
    370841 5l60:J (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P22141 27789522
    370842 5l60:K (2.7) BS01 39V 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370843 5l60:K (2.7) BS02 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370844 5l60:L (2.7) BS01 39V 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370845 5l60:N (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370846 5l60:V (2.7) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    370847 5l60:Y (2.7) BS01 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370848 5l60:Y (2.7) BS02 39V 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370849 5l60:Z (2.7) BS01 MG 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370850 5l60:b (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370851 5l61:A (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P23639 27789522
    370852 5l61:G (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370853 5l61:I (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P25451 27789522
    370854 5l61:K (2.8) BS01 6N5 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370855 5l61:K (2.8) BS02 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370856 5l61:N (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370857 5l61:V (2.8) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    370858 5l61:Y (2.8) BS01 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370859 5l61:Y (2.8) BS02 6N5 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370860 5l61:Z (2.8) BS01 MG 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370861 5l61:b (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370862 5l62:A (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P23639 27789522
    370863 5l62:G (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370864 5l62:I (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P25451 27789522
    370865 5l62:K (2.8) BS01 79P 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370866 5l62:K (2.8) BS02 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370867 5l62:N (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370868 5l62:V (2.8) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    370869 5l62:Y (2.8) BS01 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370870 5l62:Y (2.8) BS02 79P 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370871 5l62:Z (2.8) BS01 79P 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370872 5l62:b (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370873 5l63:A (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P23639 27789522
    370874 5l63:G (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370875 5l63:H (2.7) BS01 04C 3.4.25.1 GO:0004298 ... P25043 27789522
    370876 5l63:I (2.7) BS01 04C 3.4.25.1 GO:0000502 ... P25451 27789522
    370877 5l63:I (2.7) BS02 MG 3.4.25.1 GO:0000502 ... P25451 27789522
    370878 5l63:J (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P22141 27789522
    370879 5l63:K (2.7) BS01 04C 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370880 5l63:K (2.7) BS02 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370881 5l63:L (2.7) BS01 04C 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370882 5l63:N (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370883 5l63:V (2.7) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    370884 5l63:V (2.7) BS02 04C 3.4.25.1 GO:0004298 ... P25043 27789522
    370885 5l63:W (2.7) BS01 04C 3.4.25.1 GO:0000502 ... P25451 27789522
    370886 5l63:Y (2.7) BS01 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370887 5l63:Y (2.7) BS02 04C 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370888 5l63:Z (2.7) BS01 04C 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370889 5l63:Z (2.7) BS02 MG 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370890 5l63:b (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370891 5l64:A (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P23639 27789522
    370892 5l64:G (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370893 5l64:K (2.7) BS01 6NV 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370894 5l64:K (2.7) BS02 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370895 5l64:L (2.7) BS01 6NV 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370896 5l64:N (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370897 5l64:V (2.7) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    370898 5l64:Y (2.7) BS01 MG 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370899 5l64:Y (2.7) BS02 6NV 3.4.25.1 GO:0004298 ... P28074
    P30656
    27789522
    370900 5l64:Z (2.7) BS01 MG 3.4.25.1 GO:0005839 ... P20618
    P23724
    27789522
    370901 5l65:G (2.9) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370902 5l65:H (2.9) BS01 3BV 3.4.25.1 GO:0004298 ... P25043 27789522
    370903 5l65:H (2.9) BS02 3BV 3.4.25.1 GO:0004298 ... P25043 27789522
    370904 5l65:I (2.9) BS01 3BV 3.4.25.1 GO:0000502 ... P25451 27789522
    370905 5l65:I (2.9) BS02 MG 3.4.25.1 GO:0000502 ... P25451 27789522
    370906 5l65:K (2.9) BS01 3BV 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370907 5l65:K (2.9) BS02 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370908 5l65:N (2.9) BS01 3BV 3.4.25.1 GO:0000502 ... P38624 27789522
    370909 5l65:N (2.9) BS02 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370910 5l65:V (2.9) BS01 3BV 3.4.25.1 GO:0004298 ... P25043 27789522
    370911 5l65:V (2.9) BS02 3BV 3.4.25.1 GO:0004298 ... P25043 27789522
    370912 5l65:Y (2.9) BS01 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370913 5l65:Y (2.9) BS02 3BV 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370914 5l65:b (2.9) BS01 3BV 3.4.25.1 GO:0000502 ... P38624 27789522
    370915 5l66:G (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370916 5l66:H (2.8) BS01 BO2 3.4.25.1 GO:0004298 ... P25043 27789522
    370917 5l66:I (2.8) BS01 BO2 3.4.25.1 GO:0000502 ... P25451 27789522
    370918 5l66:J (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P22141 27789522
    370919 5l66:K (2.8) BS01 BO2 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370920 5l66:K (2.8) BS02 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370921 5l66:N (2.8) BS01 BO2 3.4.25.1 GO:0000502 ... P38624 27789522
    370922 5l66:N (2.8) BS02 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370923 5l66:V (2.8) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    370924 5l66:V (2.8) BS02 BO2 3.4.25.1 GO:0004298 ... P25043 27789522
    370925 5l66:Y (2.8) BS01 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370926 5l66:Y (2.8) BS02 BO2 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370927 5l66:Z (2.8) BS01 MG 3.4.25.1 GO:0005839 ... O09061
    P23724
    27789522
    370928 5l66:b (2.8) BS01 BO2 3.4.25.1 GO:0000502 ... P38624 27789522
    370929 5l67:G (2.6) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370930 5l67:I (2.6) BS01 MG 3.4.25.1 GO:0000502 ... P25451 27789522
    370931 5l67:K (2.6) BS01 39V 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370932 5l67:K (2.6) BS02 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370933 5l67:L (2.6) BS01 39V 3.4.25.1 GO:0005839 ... O09061
    P23724
    27789522
    370934 5l67:N (2.6) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370935 5l67:V (2.6) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    370936 5l67:Y (2.6) BS01 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370937 5l67:Y (2.6) BS02 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370938 5l67:Y (2.6) BS03 39V 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370939 5l67:Z (2.6) BS01 39V 3.4.25.1 GO:0005839 ... O09061
    P23724
    27789522
    370940 5l67:Z (2.6) BS02 MG 3.4.25.1 GO:0005839 ... O09061
    P23724
    27789522
    370941 5l68:G (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370942 5l68:H (2.8) BS01 6N5 3.4.25.1 GO:0004298 ... P25043 27789522
    370943 5l68:I (2.8) BS01 6N5 3.4.25.1 GO:0000502 ... P25451 27789522
    370944 5l68:I (2.8) BS02 MG 3.4.25.1 GO:0000502 ... P25451 27789522
    370945 5l68:K (2.8) BS01 6N5 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370946 5l68:K (2.8) BS02 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370947 5l68:N (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370948 5l68:V (2.8) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    370949 5l68:V (2.8) BS02 6N5 3.4.25.1 GO:0004298 ... P25043 27789522
    370950 5l68:W (2.8) BS01 6N5 3.4.25.1 GO:0000502 ... P25451 27789522
    370951 5l68:Y (2.8) BS01 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370952 5l68:Y (2.8) BS02 6N5 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370953 5l68:Z (2.8) BS01 MG 3.4.25.1 GO:0005839 ... O09061
    P23724
    27789522
    370954 5l69:G (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370955 5l69:H (2.7) BS01 79P 3.4.25.1 GO:0004298 ... P25043 27789522
    370956 5l69:I (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P25451 27789522
    370957 5l69:K (2.7) BS01 79P 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370958 5l69:K (2.7) BS02 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370959 5l69:L (2.7) BS01 79P 3.4.25.1 GO:0005839 ... O09061
    P23724
    27789522
    370960 5l69:N (2.7) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370961 5l69:V (2.7) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    370962 5l69:V (2.7) BS02 79P 3.4.25.1 GO:0004298 ... P25043 27789522
    370963 5l69:Y (2.7) BS01 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370964 5l69:Y (2.7) BS02 79P 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370965 5l69:Z (2.7) BS01 79P 3.4.25.1 GO:0005839 ... O09061
    P23724
    27789522
    370966 5l6a:G (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370967 5l6a:H (2.8) BS01 79L 3.4.25.1 GO:0004298 ... P25043 27789522
    370968 5l6a:I (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P25451 27789522
    370969 5l6a:K (2.8) BS01 79L 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370970 5l6a:K (2.8) BS02 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370971 5l6a:N (2.8) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370972 5l6a:V (2.8) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    370973 5l6a:V (2.8) BS02 79L 3.4.25.1 GO:0004298 ... P25043 27789522
    370974 5l6a:Y (2.8) BS01 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370975 5l6a:Y (2.8) BS02 79L 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370976 5l6a:Z (2.8) BS01 79L 3.4.25.1 GO:0005839 ... O09061
    P23724
    27789522
    370977 5l6b:G (2.6) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370978 5l6b:H (2.6) BS01 04C 3.4.25.1 GO:0004298 ... P25043 27789522
    370979 5l6b:I (2.6) BS01 04C 3.4.25.1 GO:0000502 ... P25451 27789522
    370980 5l6b:I (2.6) BS02 MG 3.4.25.1 GO:0000502 ... P25451 27789522
    370981 5l6b:K (2.6) BS01 04C 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370982 5l6b:K (2.6) BS02 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370983 5l6b:N (2.6) BS01 04C 3.4.25.1 GO:0000502 ... P38624 27789522
    370984 5l6b:N (2.6) BS02 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370985 5l6b:V (2.6) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    370986 5l6b:V (2.6) BS02 04C 3.4.25.1 GO:0004298 ... P25043 27789522
    370987 5l6b:W (2.6) BS01 04C 3.4.25.1 GO:0000502 ... P25451 27789522
    370988 5l6b:Y (2.6) BS01 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370989 5l6b:Y (2.6) BS02 04C 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370990 5l6b:Z (2.6) BS01 MG 3.4.25.1 GO:0005839 ... O09061
    P23724
    27789522
    370991 5l6b:b (2.6) BS01 04C 3.4.25.1 GO:0000502 ... P38624 27789522
    370992 5l6c:G (2.6) BS01 MG 3.4.25.1 GO:0000502 ... P21243 27789522
    370993 5l6c:I (2.6) BS01 MG 3.4.25.1 GO:0000502 ... P25451 27789522
    370994 5l6c:J (2.6) BS01 MG 3.4.25.1 GO:0000502 ... P22141 27789522
    370995 5l6c:K (2.6) BS01 6NV 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370996 5l6c:K (2.6) BS02 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522
    370997 5l6c:L (2.6) BS01 6NV 3.4.25.1 GO:0005839 ... O09061
    P23724
    27789522
    370998 5l6c:N (2.6) BS01 MG 3.4.25.1 GO:0000502 ... P38624 27789522
    370999 5l6c:V (2.6) BS01 MG 3.4.25.1 GO:0004298 ... P25043 27789522
    371000 5l6c:Y (2.6) BS01 MG 3.4.25.1 GO:0004298 ... P28063
    P30656
    27789522

    Reference:
  • Chengxin Zhang, Xi Zhang, Lydia Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).