SEQ2FUN

BioLiP
Download all results in tab-seperated text for 942758 receptor-ligand interactions, whose format is explained at readme.txt.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    458601 6e1x:A (1.35) BS01 SP5 2.3.1.57 GO:0000287 ... Q9KL03 N/A
    458602 6e1x:B (1.35) BS01 SP5 2.3.1.57 GO:0000287 ... Q9KL03 N/A
    458603 6e1x:C (1.35) BS01 HLG 2.3.1.57 GO:0000287 ... Q9KL03 N/A
    458604 6e1x:D (1.35) BS01 SP5 2.3.1.57 GO:0000287 ... Q9KL03 N/A
    458605 6e1y:A (1.219) BS01 HLM ? GO:0000122 ... P61964 30865883 MOAD: Kd=22nM
    BindingDB: Ki=30.8nM
    458606 6e1y:B (1.219) BS01 HLM ? GO:0000122 ... P61964 30865883 MOAD: Kd=22nM
    BindingDB: Ki=30.8nM
    458607 6e1z:A (1.1) BS01 HLP ? GO:0000122 ... P61964 30865883 MOAD: Kd=150000nM
    458608 6e1z:B (1.1) BS01 HLP ? GO:0000122 ... P61964 30865883 MOAD: Kd=150000nM
    458609 6e20:A (2.0) BS01 GAL ? GO:0001944 ... Q6TGN5 30834446
    458610 6e20:B (2.0) BS01 GAL ? GO:0001944 ... Q6TGN5 30834446
    458611 6e21:A (2.0) BS01 peptide 2.7.11.11 GO:0000122 ... P05132 30906862
    458612 6e21:A (2.0) BS02 ADP 2.7.11.11 GO:0000122 ... P05132 30906862
    458613 6e22:A (1.6) BS01 HLS ? GO:0000122 ... P61964 30865883 MOAD: Kd=1.3nM
    BindingDB: Ki=1.33nM
    458614 6e22:B (1.6) BS01 HLS ? GO:0000122 ... P61964 30865883 MOAD: Kd=1.3nM
    BindingDB: Ki=1.33nM
    458615 6e23:A (1.66) BS01 HLJ ? GO:0000122 ... P61964 30865883 MOAD: Kd=0.1nM
    BindingDB: Ki=<0.100nM
    458616 6e23:B (1.66) BS01 HLJ ? GO:0000122 ... P61964 30865883 MOAD: Kd=0.1nM
    BindingDB: Ki=<0.100nM
    458617 6e25:A (-1.00) BS01 ZN ? GO:0042981 ... Q9H257 30206119
    458618 6e2a:A (2.2) BS01 FMN 1.6.5.9 GO:0000166 ... Q9I4V0 30246917
    458619 6e2a:A (2.2) BS02 NAD 1.6.5.9 GO:0000166 ... Q9I4V0 30246917
    458620 6e2b:A (1.45) BS01 PT7 ? N/A P62992 30376305
    458621 6e2b:A (1.45) BS02 PT7 ? N/A P62992 30376305
    458622 6e2b:C (1.45) BS01 PT7 ? N/A P62992 30376305
    458623 6e2b:C (1.45) BS02 PT7 ? N/A P62992 30376305
    458624 6e2b:P (1.45) BS01 PT7 ? N/A P62992 30376305
    458625 6e2b:P (1.45) BS02 PT7 ? N/A P62992 30376305
    458626 6e2f:E (3.9) BS01 CA ? GO:0000086 ... P0DP23 30116787
    458627 6e2f:E (3.9) BS02 CA ? GO:0000086 ... P0DP23 30116787
    458628 6e2f:E (3.9) BS03 CA ? GO:0000086 ... P0DP23 30116787
    458629 6e2f:E (3.9) BS04 CA ? GO:0000086 ... P0DP23 30116787
    458630 6e2g:E (3.6) BS01 CA ? GO:0000086 ... P0DP23 30116787
    458631 6e2g:E (3.6) BS02 CA ? GO:0000086 ... P0DP23 30116787
    458632 6e2g:E (3.6) BS03 CA ? GO:0000086 ... P0DP23 30116787
    458633 6e2g:E (3.6) BS04 CA ? GO:0000086 ... P0DP23 30116787
    458634 6e2m:A (2.253) BS01 KK7 2.7.11.25 GO:0004672 ... Q99683 30024858 MOAD: ic50=2200nM
    458635 6e2m:B (2.253) BS01 KK7 2.7.11.25 GO:0004672 ... Q99683 30024858 MOAD: ic50=2200nM
    458636 6e2n:A (2.098) BS01 KK8 2.7.11.25 GO:0004672 ... Q99683 30024858 MOAD: ic50=12.5nM
    458637 6e2n:B (2.098) BS01 KK8 2.7.11.25 GO:0004672 ... Q99683 30024858 MOAD: ic50=12.5nM
    458638 6e2o:A (2.389) BS01 S0L 2.7.11.25 GO:0004672 ... Q99683 30024858 MOAD: Kd=2.9nM
    458639 6e2o:B (2.389) BS01 S0L 2.7.11.25 GO:0004672 ... Q99683 30024858 MOAD: Kd=2.9nM
    458640 6e2p:A (2.83) BS01 peptide 2.7.10.2 GO:0004715 ... O60674 30044226
    458641 6e2p:B (2.83) BS01 peptide 2.7.10.2 GO:0004715 ... O60674 30044226
    458642 6e2t:A (1.692) BS01 DP6 4.1.1.33 GO:0004163 ... Q9FD68 32769976
    458643 6e2u:A (2.05) BS01 DP6 4.1.1.33 GO:0004163 ... Q9FD68 32769976
    458644 6e2u:A (2.05) BS02 ACP 4.1.1.33 GO:0004163 ... Q9FD68 32769976
    458645 6e2v:A (2.1) BS01 DP6 4.1.1.33 GO:0004163 ... Q9FD68 32769976
    458646 6e2v:A (2.1) BS02 BEF 4.1.1.33 GO:0004163 ... Q9FD68 32769976
    458647 6e2v:A (2.1) BS03 ADP 4.1.1.33 GO:0004163 ... Q9FD68 32769976
    458648 6e2w:A (1.95) BS01 ADP 4.1.1.33 GO:0004163 ... Q9FD68 32769976
    458649 6e2w:A (1.95) BS02 DP6 4.1.1.33 GO:0004163 ... Q9FD68 32769976
    458650 6e2y:A (2.34) BS01 ADP 4.1.1.33 GO:0004163 ... Q9FD68 32769976
    458651 6e2y:A (2.34) BS02 DP6 4.1.1.33 GO:0004163 ... Q9FD68 32769976
    458652 6e2z:A6 (3.4) BS01 IDS ? GO:0019062 ... Q805N7 30602608
    458653 6e32:A1 (3.4) BS01 SGN ? GO:0019062 ... Q805N7 30602608
    458654 6e32:AN (3.4) BS01 SGN ? GO:0019062 ... Q805N7 30602608
    458655 6e33:A (1.705) BS01 dna ? GO:0000981 ... O13658 30212894
    458656 6e33:A (1.705) BS02 dna ? GO:0000981 ... O13658 30212894
    458657 6e33:A (1.705) BS03 ZN ? GO:0000981 ... O13658 30212894
    458658 6e33:A (1.705) BS04 ZN ? GO:0000981 ... O13658 30212894
    458659 6e34:AA (3.6) BS01 SGN ? GO:0019062 ... Q805N7 30602608
    458660 6e35:A (2.411) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 N/A
    458661 6e35:A (2.411) BS02 TRP 1.13.11.52 GO:0002376 ... P14902 N/A
    458662 6e35:A (2.411) BS03 ZCW 1.13.11.52 GO:0002376 ... P14902 N/A
    458663 6e35:B (2.411) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 N/A
    458664 6e35:B (2.411) BS02 TRP 1.13.11.52 GO:0002376 ... P14902 N/A
    458665 6e36:A (1.7) BS01 MG ? N/A Q9KW51 34339301
    458666 6e36:B (1.7) BS01 MG ? N/A Q9KW51 34339301
    458667 6e37:A (2.531) BS01 peptide 2.4.1.255 GO:0006493 ... O15294 31626249
    458668 6e37:A (2.531) BS02 HQV 2.4.1.255 GO:0006493 ... O15294 31626249
    458669 6e39:A1 (3.5) BS01 SGN ? GO:0019062 ... Q805N7 30602608
    458670 6e39:A5 (3.5) BS01 SGN ? GO:0019062 ... Q805N7 30602608
    458671 6e3a:A (1.4) BS01 COA 2.7.1.- GO:0000215 ... A3DJX6 30644400
    458672 6e3a:A (1.4) BS02 HQG 2.7.1.- GO:0000215 ... A3DJX6 30644400
    458673 6e3d:A (1.271) BS01 peptide ? GO:0015833 ... I6X811 31534126
    458674 6e3e:A (2.47) BS01 HQ7 ? GO:0003677 ... P51449 30652849
    458675 6e3e:B (2.47) BS01 HQ7 ? GO:0003677 ... P51449 30652849
    458676 6e3f:A (2.7) BS01 CA ? N/A Q9KW51 34339301
    458677 6e3f:A (2.7) BS02 CA ? N/A Q9KW51 34339301
    458678 6e3g:A (2.1) BS01 peptide ? GO:0003677 ... P51449 30652849
    458679 6e3g:A (2.1) BS02 HOJ ? GO:0003677 ... P51449 30652849 MOAD: ic50=44nM
    BindingDB: IC50=44nM, EC50=53nM
    458680 6e3g:B (2.1) BS01 peptide ? GO:0003677 ... P51449 30652849
    458681 6e3g:B (2.1) BS02 HOJ ? GO:0003677 ... P51449 30652849 MOAD: ic50=44nM
    BindingDB: IC50=44nM, EC50=53nM
    458682 6e3i:A (1.481) BS01 peptide ? GO:0042981 ... Q16548 30322927
    458683 6e3j:A (1.482) BS01 peptide ? GO:0042981 ... Q16548 30322927
    458684 6e3k:E (3.25) BS01 CYS ? N/A P38484 30814731
    458685 6e3k:I (3.25) BS01 CYS ? N/A P38484 30814731
    458686 6e3l:E (3.8) BS01 CYS ? N/A P38484 30814731
    458687 6e3l:I (3.8) BS01 CYS ? N/A P38484 30814731
    458688 6e3m:A (2.65) BS01 MN 3.1.-.- GO:0003723 ... C3W5S0 31536340
    458689 6e3m:A (2.65) BS02 MN 3.1.-.- GO:0003723 ... C3W5S0 31536340
    458690 6e3m:A (2.65) BS03 HOG 3.1.-.- GO:0003723 ... C3W5S0 31536340
    458691 6e3n:A (3.19) BS01 MN 3.1.-.- GO:0003723 ... C3W5S0 31536340
    458692 6e3n:A (3.19) BS02 MN 3.1.-.- GO:0003723 ... C3W5S0 31536340
    458693 6e3n:A (3.19) BS03 HNS 3.1.-.- GO:0003723 ... C3W5S0 31536340
    458694 6e3o:A (3.19) BS01 MN 3.1.-.- GO:0003723 ... C3W5S0 31536340
    458695 6e3o:A (3.19) BS02 MN 3.1.-.- GO:0003723 ... C3W5S0 31536340
    458696 6e3o:A (3.19) BS03 HNY 3.1.-.- GO:0003723 ... C3W5S0 31536340
    458697 6e3p:A (2.8) BS01 MN 3.1.-.- GO:0003723 ... C3W5S0 31536340
    458698 6e3p:A (2.8) BS02 MN 3.1.-.- GO:0003723 ... C3W5S0 31536340
    458699 6e3p:A (2.8) BS03 HO1 3.1.-.- GO:0003723 ... C3W5S0 31536340
    458700 6e3p:A (2.8) BS04 HO1 3.1.-.- GO:0003723 ... C3W5S0 31536340
    458701 6e3r:A (2.26) BS01 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458702 6e3r:A (2.26) BS02 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458703 6e3r:A (2.26) BS03 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458704 6e3s:B (3.0) BS01 79A ? GO:0003700 ... P97481 30804532
    458705 6e3t:B (3.0) BS01 HO7 ? GO:0003700 ... P97481 30804532
    458706 6e3u:B (2.85) BS01 HNJ ? GO:0003700 ... P97481 30804532
    458707 6e3v:A (1.96) BS01 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458708 6e3v:A (1.96) BS02 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458709 6e3v:A (1.96) BS03 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458710 6e3v:A (1.96) BS04 MG 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458711 6e3v:A (1.96) BS05 MG 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458712 6e3v:A (1.96) BS06 1FZ 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458713 6e3w:A (2.02) BS01 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458714 6e3w:A (2.02) BS02 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458715 6e3w:A (2.02) BS03 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458716 6e3w:A (2.02) BS04 MG 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458717 6e3w:A (2.02) BS05 MG 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458718 6e3w:A (2.02) BS06 XG4 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 30817143
    458719 6e3x:A (2.65) BS01 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 N/A
    458720 6e3x:A (2.65) BS02 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 N/A
    458721 6e3x:A (2.65) BS03 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 N/A
    458722 6e3x:A (2.65) BS04 MG 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 N/A
    458723 6e3x:A (2.65) BS05 MG 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 N/A
    458724 6e3x:A (2.65) BS06 DZ4 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 N/A
    458725 6e3z:A (1.94) BS01 HRV 3.4.23.46 GO:0004190 ... P56817 N/A
    458726 6e3z:B (1.94) BS01 HRV 3.4.23.46 GO:0004190 ... P56817 N/A
    458727 6e3z:C (1.94) BS01 HRV 3.4.23.46 GO:0004190 ... P56817 N/A
    458728 6e3z:C (1.94) BS02 HRV 3.4.23.46 GO:0004190 ... P56817 N/A
    458729 6e40:A (2.306) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458730 6e40:A (2.306) BS02 BBJ 1.13.11.52 GO:0002376 ... P14902 30387777 BindingDB: IC50=72nM, EC50=8.0nM, Kd=3460nM
    458731 6e40:B (2.306) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458732 6e40:B (2.306) BS02 BBJ 1.13.11.52 GO:0002376 ... P14902 30387777 BindingDB: IC50=72nM, EC50=8.0nM, Kd=3460nM
    458733 6e40:C (2.306) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458734 6e40:D (2.306) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458735 6e40:D (2.306) BS02 BBJ 1.13.11.52 GO:0002376 ... P14902 30387777 BindingDB: IC50=72nM, EC50=8.0nM, Kd=3460nM
    458736 6e41:A (2.291) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458737 6e41:A (2.291) BS02 HQS 1.13.11.52 GO:0002376 ... P14902 30387777 BindingDB: IC50=2.8nM
    458738 6e41:A (2.291) BS03 HQS 1.13.11.52 GO:0002376 ... P14902 30387777 BindingDB: IC50=2.8nM
    458739 6e41:B (2.291) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458740 6e41:B (2.291) BS02 HQS 1.13.11.52 GO:0002376 ... P14902 30387777 BindingDB: IC50=2.8nM
    458741 6e41:C (2.291) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458742 6e41:C (2.291) BS02 HQS 1.13.11.52 GO:0002376 ... P14902 30387777 BindingDB: IC50=2.8nM
    458743 6e41:C (2.291) BS03 HQS 1.13.11.52 GO:0002376 ... P14902 30387777 BindingDB: IC50=2.8nM
    458744 6e41:D (2.291) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458745 6e41:D (2.291) BS02 HQS 1.13.11.52 GO:0002376 ... P14902 30387777 BindingDB: IC50=2.8nM
    458746 6e42:A (2.103) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458747 6e42:A (2.103) BS02 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458748 6e42:A (2.103) BS03 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458749 6e42:A (2.103) BS04 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458750 6e42:A (2.103) BS05 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458751 6e42:B (2.103) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458752 6e42:B (2.103) BS02 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458753 6e42:B (2.103) BS03 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458754 6e42:B (2.103) BS04 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458755 6e42:B (2.103) BS05 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458756 6e42:C (2.103) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458757 6e42:C (2.103) BS02 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458758 6e42:C (2.103) BS03 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458759 6e42:C (2.103) BS04 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458760 6e42:C (2.103) BS05 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458761 6e42:D (2.103) BS01 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458762 6e42:D (2.103) BS02 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458763 6e42:D (2.103) BS03 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458764 6e42:D (2.103) BS04 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458765 6e42:D (2.103) BS05 HQJ 1.13.11.52 GO:0002376 ... P14902 30387777
    458766 6e43:A (1.705) BS01 HQM 1.13.11.52 GO:0002376 ... P14902 30387777
    458767 6e43:B (1.705) BS01 HQM 1.13.11.52 GO:0002376 ... P14902 30387777
    458768 6e43:C (1.705) BS01 HQM 1.13.11.52 GO:0002376 ... P14902 30387777
    458769 6e43:D (1.705) BS01 HQM 1.13.11.52 GO:0002376 ... P14902 30387777
    458770 6e44:A (1.903) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458771 6e44:B (1.903) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458772 6e44:C (1.903) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458773 6e44:D (1.903) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458774 6e45:A (2.0) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458775 6e45:B (2.0) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458776 6e45:C (2.0) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458777 6e45:D (2.0) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458778 6e46:A (2.09) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458779 6e46:A (2.09) BS02 TRP 1.13.11.52 GO:0002376 ... P14902 30387777
    458780 6e46:B (2.09) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458781 6e46:B (2.09) BS02 TRP 1.13.11.52 GO:0002376 ... P14902 30387777
    458782 6e46:C (2.09) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458783 6e46:C (2.09) BS02 TRP 1.13.11.52 GO:0002376 ... P14902 30387777
    458784 6e46:D (2.09) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 30387777
    458785 6e46:D (2.09) BS02 TRP 1.13.11.52 GO:0002376 ... P14902 30387777
    458786 6e47:A (1.95) BS01 MG ? N/A Q80J94 30194229
    458787 6e47:A (1.95) BS02 MG ? N/A Q80J94 30194229
    458788 6e47:A (1.95) BS03 CHO ? N/A Q80J94 30194229
    458789 6e47:A (1.95) BS04 CHO ? N/A Q80J94 30194229
    458790 6e47:A (1.95) BS05 MG ? N/A Q80J94 30194229
    458791 6e47:B (1.95) BS01 CHO ? N/A Q80J94 30194229
    458792 6e47:B (1.95) BS02 CHO ? N/A Q80J94 30194229
    458793 6e47:B (1.95) BS03 MG ? N/A Q80J94 30194229
    458794 6e47:B (1.95) BS04 MG ? N/A Q80J94 30194229
    458795 6e47:B (1.95) BS05 MG ? N/A Q80J94 30194229
    458796 6e47:F (1.95) BS01 MG ? N/A Q6SJQ7 30194229
    458797 6e47:G (1.95) BS01 MG ? N/A Q6SJQ7 30194229
    458798 6e48:A (1.801) BS01 4OA ? N/A Q80J94 30194229
    458799 6e48:A (1.801) BS02 CA ? N/A Q80J94 30194229
    458800 6e48:A (1.801) BS03 CA ? N/A Q80J94 30194229

    Reference:
  • Chengxin Zhang, Xi Zhang, Lydia Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).