SEQ2FUN

BioLiP
Download all results in tab-seperated text for 942758 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    513401 6nb1:E (1.9) BS02 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513402 6nb1:F (1.9) BS01 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513403 6nb1:F (1.9) BS02 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513404 6nb1:G (1.9) BS01 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513405 6nb1:G (1.9) BS02 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513406 6nb1:H (1.9) BS01 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513407 6nb1:H (1.9) BS02 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513408 6nb1:I (1.9) BS01 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513409 6nb1:I (1.9) BS02 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513410 6nb1:J (1.9) BS01 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513411 6nb1:J (1.9) BS02 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513412 6nb1:K (1.9) BS01 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513413 6nb1:K (1.9) BS02 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513414 6nb1:L (1.9) BS01 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513415 6nb1:L (1.9) BS02 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513416 6nb1:M (1.9) BS01 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513417 6nb1:M (1.9) BS02 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513418 6nb1:N (1.9) BS01 KHS 3.4.21.92 GO:0004176 ... P0A6G7 31925204
    513419 6nb2:A (1.85) BS01 2PG 4.2.1.11 GO:0000015 ... Q5ZTX1 N/A
    513420 6nb2:A (1.85) BS02 MG 4.2.1.11 GO:0000015 ... Q5ZTX1 N/A
    513421 6nb2:B (1.85) BS01 2PG 4.2.1.11 GO:0000015 ... Q5ZTX1 N/A
    513422 6nb2:B (1.85) BS02 MG 4.2.1.11 GO:0000015 ... Q5ZTX1 N/A
    513423 6nb3:A (3.5) BS01 MAN ? GO:0016020 ... A0A140AYW5 30712865
    513424 6nb4:A (3.6) BS01 MAN ? GO:0016020 ... A0A140AYW5 30712865
    513425 6nba:A (2.495) BS01 P1T 4.4.1.1
    4.4.1.2
    GO:0004123 ... P32929 31160338
    513426 6nba:A (2.495) BS02 P1T 4.4.1.1
    4.4.1.2
    GO:0004123 ... P32929 31160338
    513427 6nba:B (2.495) BS01 P1T 4.4.1.1
    4.4.1.2
    GO:0004123 ... P32929 31160338
    513428 6nba:B (2.495) BS02 P1T 4.4.1.1
    4.4.1.2
    GO:0004123 ... P32929 31160338
    513429 6nba:C (2.495) BS01 P1T 4.4.1.1
    4.4.1.2
    GO:0004123 ... P32929 31160338
    513430 6nba:C (2.495) BS02 P1T 4.4.1.1
    4.4.1.2
    GO:0004123 ... P32929 31160338
    513431 6nba:D (2.495) BS01 P1T 4.4.1.1
    4.4.1.2
    GO:0004123 ... P32929 31160338
    513432 6nba:D (2.495) BS02 P1T 4.4.1.1
    4.4.1.2
    GO:0004123 ... P32929 31160338
    513433 6nbb:A (2.9) BS01 NAD 1.1.1.1 GO:0004022 ... P00327 30833564
    513434 6nbb:A (2.9) BS02 ZN 1.1.1.1 GO:0004022 ... P00327 30833564
    513435 6nbb:A (2.9) BS03 ZN 1.1.1.1 GO:0004022 ... P00327 30833564
    513436 6nbb:B (2.9) BS01 NAD 1.1.1.1 GO:0004022 ... P00327 30833564
    513437 6nbb:B (2.9) BS02 ZN 1.1.1.1 GO:0004022 ... P00327 30833564
    513438 6nbb:B (2.9) BS03 ZN 1.1.1.1 GO:0004022 ... P00327 30833564
    513439 6nbc:A (2.8) BS01 HEM ? GO:0004601 ... P69905 30833564
    513440 6nbc:B (2.8) BS01 HEM ? GO:0004601 ... P68871 30833564
    513441 6nbc:C (2.8) BS01 HEM ? GO:0004601 ... P69905 30833564
    513442 6nbc:D (2.8) BS01 HEM ? GO:0004601 ... P68871 30833564
    513443 6nbd:A (3.2) BS01 HEM ? GO:0004601 ... P69905 30833564
    513444 6nbd:B (3.2) BS01 HEM ? GO:0004601 ... P68871 30833564
    513445 6nbd:C (3.2) BS01 HEM ? GO:0004601 ... P69905 30833564
    513446 6nbd:D (3.2) BS01 HEM ? GO:0004601 ... P68871 30833564
    513447 6nbe:A (2.0) BS01 ATP 3.6.4.- GO:0000287 ... P68135 32284999
    513448 6nbe:A (2.0) BS02 LAB 3.6.4.- GO:0000287 ... P68135 32284999 BindingDB: IC50=8470nM
    513449 6nbe:N (2.0) BS01 COA 2.3.1.- GO:0008080 ... Q93015 32284999
    513450 6nbf:R (3.0) BS01 CLR ? GO:0004888 ... Q03431 30975883
    513451 6nbf:R (3.0) BS02 CLR ? GO:0004888 ... Q03431 30975883
    513452 6nbf:R (3.0) BS03 CLR ? GO:0004888 ... Q03431 30975883
    513453 6nbf:R (3.0) BS04 CLR ? GO:0004888 ... Q03431 30975883
    513454 6nbf:R (3.0) BS05 CLR ? GO:0004888 ... Q03431 30975883
    513455 6nbh:R (3.5) BS01 CLR ? GO:0004888 ... Q03431 30975883
    513456 6nbh:R (3.5) BS02 CLR ? GO:0004888 ... Q03431 30975883
    513457 6nbh:R (3.5) BS03 CLR ? GO:0004888 ... Q03431 30975883
    513458 6nbh:R (3.5) BS04 CLR ? GO:0004888 ... Q03431 30975883
    513459 6nbh:R (3.5) BS05 CLR ? GO:0004888 ... Q03431 30975883
    513460 6nbi:R (4.0) BS01 CLR ? GO:0004888 ... Q03431 30975883
    513461 6nbj:A (2.94) BS01 rna 2.3.1.234 GO:0000049 ... P43122 N/A
    513462 6nbj:A (2.94) BS02 ZN 2.3.1.234 GO:0000049 ... P43122 N/A
    513463 6nbj:A (2.94) BS03 AMP 2.3.1.234 GO:0000049 ... P43122 N/A
    513464 6nbj:B (2.94) BS01 rna 2.3.1.234 GO:0000049 ... P43122 N/A
    513465 6nbj:B (2.94) BS02 ATP 2.3.1.234 GO:0000049 ... P43122 N/A
    513466 6nbj:B (2.94) BS03 ZN 2.3.1.234 GO:0000049 ... P43122 N/A
    513467 6nbj:B (2.94) BS04 AMP 2.3.1.234 GO:0000049 ... P43122 N/A
    513468 6nbk:A (1.91) BS01 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513469 6nbk:A (1.91) BS02 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513470 6nbk:A (1.91) BS03 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513471 6nbk:B (1.91) BS01 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513472 6nbk:B (1.91) BS02 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513473 6nbk:B (1.91) BS03 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513474 6nbk:C (1.91) BS01 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513475 6nbk:C (1.91) BS02 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513476 6nbk:D (1.91) BS01 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513477 6nbk:D (1.91) BS02 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513478 6nbk:E (1.91) BS01 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513479 6nbk:E (1.91) BS02 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513480 6nbk:F (1.91) BS01 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513481 6nbk:F (1.91) BS02 MN 3.5.3.1 GO:0000050 ... W8YSI5 N/A
    513482 6nbl:A (2.15) BS01 HEM 1.14.15.1 GO:0004497 ... P00183 30672701
    513483 6nbl:A (2.15) BS02 CAM 1.14.15.1 GO:0004497 ... P00183 30672701
    513484 6nbl:A (2.15) BS03 CA 1.14.15.1 GO:0004497 ... P00183 30672701
    513485 6nbl:B (2.15) BS01 HEM 1.14.15.1 GO:0004497 ... P00183 30672701
    513486 6nbl:B (2.15) BS02 CAM 1.14.15.1 GO:0004497 ... P00183 30672701
    513487 6nbl:B (2.15) BS03 CA 1.14.15.1 GO:0004497 ... P00183 30672701
    513488 6nbl:C (2.15) BS01 FES ? GO:0005515 ... P00259 30672701
    513489 6nbl:D (2.15) BS01 FES ? GO:0005515 ... P00259 30672701
    513490 6nbm:A (1.9) BS01 MG N/A GO:0000015 ... N/A N/A
    513491 6nbm:B (1.9) BS01 MG N/A GO:0000015 ... N/A N/A
    513492 6nbn:A (-1.00) BS01 ACD ? GO:0005549 ... Q1HRL7 32094450
    513493 6nbo:A (1.95) BS01 ZN 3.5.4.42 GO:0016787 ... A0A0H3KPJ4 N/A
    513494 6nbo:A (1.95) BS02 ZN 3.5.4.42 GO:0016787 ... A0A0H3KPJ4 N/A
    513495 6nbp:A (1.7) BS01 0FX ? GO:0004479 ... A0A4P1LYI6 30666752
    513496 6nbp:A (1.7) BS02 FON ? GO:0004479 ... A0A4P1LYI6 30666752
    513497 6nbq:I (3.1) BS01 SF4 7.1.1.- GO:0005506 ... Q8DL31 30742075
    513498 6nbq:I (3.1) BS02 SF4 7.1.1.- GO:0005506 ... Q8DL31 30742075
    513499 6nbq:K (3.1) BS01 SF4 7.1.1.- GO:0005506 ... Q8DKZ4 30742075
    513500 6nbr:A (2.8) BS01 NAP ? GO:0000166 ... A0A4Y5QR90 31332312
    513501 6nbr:B (2.8) BS01 NAP ? GO:0000166 ... A0A4Y5QR90 31332312
    513502 6nbr:C (2.8) BS01 NAP ? GO:0000166 ... A0A4Y5QR90 31332312
    513503 6nbr:D (2.8) BS01 NAP ? GO:0000166 ... A0A4Y5QR90 31332312
    513504 6nbs:A (1.9) BS01 KJ7 2.7.11.24 GO:0000165 ... P28482 31058487
    513505 6nbs:A (1.9) BS02 KJ4 2.7.11.24 GO:0000165 ... P28482 31058487
    513506 6nbw:A (2.5) BS01 ATP 3.6.4.- GO:0000776 ... P60709 32284999
    513507 6nbw:A (2.5) BS02 LAB 3.6.4.- GO:0000776 ... P60709 32284999
    513508 6nbw:N (2.5) BS01 SOP 2.3.1.- GO:0008080 ... Q93015 32284999
    513509 6nbx:I (3.5) BS01 SF4 7.1.1.- GO:0005506 ... Q8DL31 30742075
    513510 6nbx:I (3.5) BS02 SF4 7.1.1.- GO:0005506 ... Q8DL31 30742075
    513511 6nbx:K (3.5) BS01 SF4 7.1.1.- GO:0005506 ... Q8DKZ4 30742075
    513512 6nby:I (3.1) BS01 SF4 7.1.1.- GO:0005506 ... Q8DL31 30742075
    513513 6nby:I (3.1) BS02 SF4 7.1.1.- GO:0005506 ... Q8DL31 30742075
    513514 6nby:K (3.1) BS01 SF4 7.1.1.- GO:0005506 ... Q8DKZ4 30742075
    513515 6nc1:A (1.598) BS01 GDP 3.6.5.4 GO:0005525 ... P10121 31520694
    513516 6nc4:A (1.6) BS01 GNP 3.6.5.4 GO:0005525 ... P10121 31520694
    513517 6nc4:B (1.6) BS01 GDP 3.6.5.4 GO:0005525 ... P10121 31520694
    513518 6nc5:A (2.074) BS01 ZN N/A N/A N/A 32542533
    513519 6nc5:A (2.074) BS02 ZN N/A N/A N/A 32542533
    513520 6nc5:A (2.074) BS03 ZN N/A N/A N/A 32542533
    513521 6nc5:A (2.074) BS04 ZN N/A N/A N/A 32542533
    513522 6nc6:A (3.2) BS01 ZN ? GO:0005886 ... B7IE18 30988294
    513523 6nc6:B (3.2) BS01 ZN ? GO:0005886 ... B7IE18 30988294
    513524 6nca:A (3.3) BS01 peptide ? N/A P04439 31765434
    513525 6nca:B (3.3) BS01 peptide ? N/A P04439 31765434
    513526 6nca:C (3.3) BS01 peptide ? N/A P04439 31765434
    513527 6nca:D (3.3) BS01 peptide ? N/A P04439 31765434
    513528 6nca:E (3.3) BS01 peptide ? N/A P04439 31765434
    513529 6nca:F (3.3) BS01 peptide ? N/A P04439 31765434
    513530 6nca:G (3.3) BS01 peptide ? N/A P04439 31765434
    513531 6nca:H (3.3) BS01 peptide ? N/A P04439 31765434
    513532 6nca:I (3.3) BS01 peptide ? N/A P04439 31765434
    513533 6nca:J (3.3) BS01 peptide ? N/A P04439 31765434
    513534 6nca:K (3.3) BS01 peptide ? N/A P04439 31765434
    513535 6nca:L (3.3) BS01 peptide ? N/A P04439 31765434
    513536 6nca:M (3.3) BS01 peptide ? N/A P04439 31765434
    513537 6nca:N (3.3) BS01 peptide ? N/A P04439 31765434
    513538 6nca:O (3.3) BS01 peptide ? N/A P04439 31765434
    513539 6nca:P (3.3) BS01 peptide ? N/A P04439 31765434
    513540 6nca:Q (3.3) BS01 peptide ? N/A P04439 31765434
    513541 6nca:R (3.3) BS01 peptide ? N/A P04439 31765434
    513542 6nca:R (3.3) BS02 peptide ? N/A P04439 31765434
    513543 6nca:S (3.3) BS01 peptide ? N/A P04439 31765434
    513544 6nca:T (3.3) BS01 peptide ? N/A P04439 31765434
    513545 6nce:A (2.598) BS01 dna ? GO:0003700 ... O00409 30826165
    513546 6nce:A (2.598) BS02 dna ? GO:0003700 ... O00409 30826165
    513547 6nce:A (2.598) BS03 MG ? GO:0003700 ... O00409 30826165
    513548 6ncf:A (2.871) BS01 FE2 1.13.11.-
    1.13.11.34
    GO:0001676 ... P09917 32393899
    513549 6ncf:B (2.871) BS01 FE2 1.13.11.-
    1.13.11.34
    GO:0001676 ... P09917 32393899
    513550 6ncf:B (2.871) BS02 AF7 1.13.11.-
    1.13.11.34
    GO:0001676 ... P09917 32393899 BindingDB: IC50=35600nM
    513551 6ncf:C (2.871) BS01 FE2 1.13.11.-
    1.13.11.34
    GO:0001676 ... P09917 32393899
    513552 6ncf:D (2.871) BS01 FE2 1.13.11.-
    1.13.11.34
    GO:0001676 ... P09917 32393899
    513553 6ncg:A (2.45) BS01 KJD 2.7.11.1 GO:0004672 ... Q86Y07 N/A BindingDB: Kd=401nM
    513554 6ncg:B (2.45) BS01 KJD 2.7.11.1 GO:0004672 ... Q86Y07 N/A BindingDB: Kd=401nM
    513555 6nch:B (2.0) BS01 RB5 ? N/A Q81EE8 30704096
    513556 6nci:B (2.08) BS01 RB5 ? N/A Q81EE8 30704096
    513557 6ncj:A (2.0) BS01 KJJ ? GO:0003676 ... F2WR52 30609350 MOAD: ic50=0.024uM
    513558 6nck:A (2.7) BS01 CU 1.14.17.3
    4.3.2.5
    GO:0003824 ... P14925 30704096
    513559 6ncm:A (2.704) BS01 dna ? GO:0003700 ... O00409 30826165
    513560 6ncm:A (2.704) BS02 dna ? GO:0003700 ... O00409 30826165
    513561 6ncm:A (2.704) BS03 MG ? GO:0003700 ... O00409 30826165
    513562 6ncm:B (2.704) BS01 dna ? GO:0003700 ... O00409 30826165
    513563 6ncm:B (2.704) BS02 MG ? GO:0003700 ... O00409 30826165
    513564 6ncn:A (1.82) BS01 KJM ? GO:0005576 ... P02649 30933499 MOAD: Kd=900uM
    513565 6nco:A (1.707) BS01 KQP ? GO:0005576 ... P02649 30933499 MOAD: Kd=30uM
    513566 6ncp:B (2.76) BS01 peptide N/A N/A N/A 31194940
    513567 6ncp:B (2.76) BS02 GLY N/A N/A N/A 31194940
    513568 6ncp:C (2.76) BS01 peptide N/A N/A N/A 31194940
    513569 6ncp:D (2.76) BS01 peptide N/A N/A N/A 31194940
    513570 6ncr:A (1.75) BS01 TRP 6.1.1.2 GO:0000166 ... O84589 N/A
    513571 6ncr:A (1.75) BS02 CA 6.1.1.2 GO:0000166 ... O84589 N/A
    513572 6ncr:B (1.75) BS01 TRP 6.1.1.2 GO:0000166 ... O84589 N/A
    513573 6ncs:A (1.8) BS01 MN ? GO:0016051 ... Q04TM5 N/A
    513574 6ncs:B (1.8) BS01 MN ? GO:0016051 ... Q04TM5 N/A
    513575 6ncx:A (2.25) BS01 ADA 3.2.1.31 GO:0004553 ... A0A1E3AEY6 30729778
    513576 6ncx:B (2.25) BS01 ADA 3.2.1.31 GO:0004553 ... A0A1E3AEY6 30729778
    513577 6ncx:C (2.25) BS01 ADA 3.2.1.31 GO:0004553 ... A0A1E3AEY6 30729778
    513578 6ncx:D (2.25) BS01 ADA 3.2.1.31 GO:0004553 ... A0A1E3AEY6 30729778
    513579 6ncz:A (2.2) BS01 FYJ 3.2.1.31 GO:0004553 ... A0A174EHD1 30729778
    513580 6ncz:B (2.2) BS01 FYJ 3.2.1.31 GO:0004553 ... A0A174EHD1 30729778
    513581 6ncz:C (2.2) BS01 FYJ 3.2.1.31 GO:0004553 ... A0A174EHD1 30729778
    513582 6ncz:D (2.2) BS01 FYJ 3.2.1.31 GO:0004553 ... A0A174EHD1 30729778
    513583 6ncz:E (2.2) BS01 FYJ 3.2.1.31 GO:0004553 ... A0A174EHD1 30729778
    513584 6ncz:F (2.2) BS01 FYJ 3.2.1.31 GO:0004553 ... A0A174EHD1 30729778
    513585 6nd2:X (2.243) BS01 G8J 1.5.1.3 GO:0004146 ... P0A017 31201212 BindingDB: Ki=4.5nM
    513586 6nd2:X (2.243) BS02 XNP 1.5.1.3 GO:0004146 ... P0A017 31201212
    513587 6nd3:A (2.364) BS01 BTL 4.3.99.4 GO:0003824 ... Q30W70 30557011
    513588 6nd3:B (2.364) BS01 BTL 4.3.99.4 GO:0003824 ... Q30W70 30557011
    513589 6nd3:C (2.364) BS01 BTL 4.3.99.4 GO:0003824 ... Q30W70 30557011
    513590 6nd3:D (2.364) BS01 BTL 4.3.99.4 GO:0003824 ... Q30W70 30557011
    513591 6nd3:E (2.364) BS01 BTL 4.3.99.4 GO:0003824 ... Q30W70 30557011
    513592 6nd3:F (2.364) BS01 BTL 4.3.99.4 GO:0003824 ... Q30W70 30557011
    513593 6nd3:G (2.364) BS01 BTL 4.3.99.4 GO:0003824 ... Q30W70 30557011
    513594 6nd3:H (2.364) BS01 BTL 4.3.99.4 GO:0003824 ... Q30W70 30557011
    513595 6nd4:H (4.3) BS01 rna ? GO:0000462 ... Q02931 31206356
    513596 6nd4:J (4.3) BS01 rna ? GO:0000462 ... Q04305 31206356
    513597 6nd4:L (4.3) BS01 rna ? GO:0000462 ... Q04177 31206356
    513598 6nd4:N (4.3) BS01 rna ? GO:0000462 ... Q06679 31206356
    513599 6nd4:N (4.3) BS02 peptide ? GO:0000462 ... Q06679 31206356
    513600 6nd4:O (4.3) BS01 rna ? GO:0000028 ... P25635 31206356

    Reference:
  • Chengxin Zhang, Xi Zhang, Lydia Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).