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# DMFold results for P60608

#### [Click result.zip to download all results on this page]

Input Sequence in FASTA format

>P60608 (527 residues) MNSPCDRLQQFIQVLLEESWSFPSFANTLHWPENLLSYIDELVWQGSLQNFHQHEVRFDK PPLRLPLTGFSSLTENWSSRQAVSSRLVATAASPPAGCQAPIAFLGLKFSSLGPARKNPA LCFLYDQSNSKCNTSWVKENVGCPWHWCNIHEALIRTEKGSDPMFYVNTSTGGRDGFNGF NLQISDPWDPRWASGVDGGLYEHKTFMYPVAKIRIARTLKTTVTGLSDLASSIQSAEKEL TSQLQPAADQAKSSRFSWLTLISEGAQLLQSTGVQNLSHCFLCAALRRPPLVAVPLPTPF NYTINSSTPIPPVPKGQVPLFSDPIRHKFPFCYSTPNASWCNQTRMLTSTPAPPRGYFWC NSTLTKVLNSTGNHTLCLPISLIPGLTLYSQDELSHLLAWTEPRPQNKSKWAIFLPLVLG ISLASSLVASGLGKGALTHSIQTSQDLSTHLQLAIEASAESLDSLQRQITTVAQVAAQNR QALDLLMAEKGRTCLFLQEECCYYLNESGVVENSLQTLKKKKSSKRS

Predicted Contact and Distance Map

Contact Map | Distance Map

Top 5 final models from DMFold

Two sets of DMFold models are listed: 'v1' refers to the models built with the 'pLDDT' pre-trained parameters and 'v2' to the models built with the 'pTM' pre-trained parameters. On average, the 'v1' models have a slightly higher pLDDT score than the 'v2' models, and users are suggested to select the models with a higher pLDDT score.
Final models from DMFold with parameters v1

DMFold models

Click to view | Rank | Download | pLDDT scorea
| 1 | model1.pdb.gz | 0.6966
| 2 | model2.pdb.gz | 0.6877
| 3 | model3.pdb.gz | 0.6740
| 4 | model4.pdb.gz | 0.6739
| 5 | model5.pdb.gz | 0.6682
(a) | This set of models (v1) is predicted by DMFold with the 'pLDDT' pre-trained parameters, which is slightly better than the models (v2) predicted by DMFold with the 'pTM' pre-trained parameters in average meaning based on our benchmark results. However, no matter with which version, the model with the higher pLDDT score should be always selected. The model confidence is quantitatified and ranked by predicted LDDT (pLDDT) score, and higher pLDDT score signifies higher model confidence. Usually, pLDDT score>0.7 indicates a correct fold.

Residue-level pLDDT scores and alignment depth

Residue-level pLDDT scores of model1 (v1) and alignment depth of the MSA

Final models from DMFold with parameters v2

DMFold models

Click to view | Rank | Download | pLDDT scorea
| 1 | model1_v2.pdb.gz | 0.6882
| 2 | model2_v2.pdb.gz | 0.6635
| 3 | model3_v2.pdb.gz | 0.6617
| 4 | model4_v2.pdb.gz | 0.6573
| 5 | model5_v2.pdb.gz | 0.6349
(a) | This set of models (v2) is predicted by DMFold with the 'pTM' pre-trained parameters, which is slightly worse than the models (v1) predicted by DMFold with the 'pLDDT' pre-trained parameters in average meaning based on our benchmark results. However, no matter with which version, the model with the higher pLDDT score should be always selected. The model confidence is quantitatified and ranked by predicted LDDT (pLDDT) score, and higher pLDDT score signifies higher model confidence. Usually, pLDDT score>0.7 indicates a correct fold.

Residue-level pLDDT scores and alignment depth

Residue-level pLDDT scores of model1 (v2) and alignment depth of the MSA

Predicted aligned error

The color at position (x, y) indicates DMFold's expected position error at residue x in Angstroms, when the predicted and true structures are aligned on residue y.
PAE |

References:
1. | Wei Zheng, Qiqige Wuyun, Yang Li, Chengxin Zhang, P Lydia Freddolino, Yang Zhang. Improving deep learning protein monomer and complex structure prediction using DeepMSA2 with huge metagenomics data. Submitted (2023).