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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Type-1 angiotensin II receptor
Species	Oryctolagus cuniculus (Rabbit)
Gene	AGTR1
Synonym	Angiotensin II type-1 receptor AT1
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
UniProt	P34976
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3948
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL15517
Molecular formula	C26H26ClN3O3
IUPAC name	2-[2-chloro-4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]phenoxy]-2-(2-methylphenyl)acetic acid
Molecular weight	463.962
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.1
Synonyms	[2-Chloro-4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenoxy]-o-tolyl-acetic acid BDBM50284453 L005510 SCHEMBL9127009
Inchi Key	APSWMQVSEDQAFN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H26ClN3O3/c1-5-22-29-23-16(3)12-17(4)28-25(23)30(22)14-18-10-11-21(20(27)13-18)33-24(26(31)32)19-9-7-6-8-15(19)2/h6-13,24H,5,14H2,1-4H3,(H,31,32)
PubChem CID	15229605
ChEMBL	CHEMBL15517
IUPHAR	N/A
BindingDB	50284453
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	3.4 nM	, Bioorg. Med. Chem. Lett., (1995) 5:11:1151	BindingDB,ChEMBL

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