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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Bombesin receptor subtype-3
Species	Mus musculus (Mouse)
Gene	Brs3
Synonym	bb3 BB3 receptor bombesin like receptor 3 bombesin receptor subtype-3 BRS-3
Disease	N/A for non-human GPCRs
Length	399
Amino acid sequence	MSQRQSQSPNQTLISITNDTETSSSVVSNDTTHKGWTGDNSPGIEALCAIYITYAGIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGKVGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPPNAILKTCAKAGGIWIVSMIFALPEAIFSNVYTFQDPNRNVTFESCNSYPISERLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIAKTVLVLVALFALCWLPNHLLYLYHSFTYESYANHSDVPFVIIIFSRVLAFSNSCVNPFALYWLSKTFQQHFKAQLCCLKAEQPEPPLGDIPLNNLTVMGRVPATGSAHVSEISVTLFSGSSAKKGEDKV
UniProt	O54798
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075140
IUPHAR	40
DrugBank	N/A

Ligand

Name	CHEMBL1089511
Molecular formula	C19H24N4S
IUPAC name	4-[4-[2-[5-(2,2-dimethylbutyl)-1H-imidazol-2-yl]ethyl]phenyl]thiadiazole
Molecular weight	340.489
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.1
Synonyms	BDBM50314978 4-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1,2,3-thiadiazole
Inchi Key	APZIDMYPKSRDGT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H24N4S/c1-4-19(2,3)11-16-12-20-18(21-16)10-7-14-5-8-15(9-6-14)17-13-24-23-22-17/h5-6,8-9,12-13H,4,7,10-11H2,1-3H3,(H,20,21)
PubChem CID	46884659
ChEMBL	CHEMBL1089511
IUPHAR	N/A
BindingDB	50314978
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	11.0 nM	PMID20219372	BindingDB,ChEMBL
EC50	109.0 nM	PMID20219372	BindingDB,ChEMBL

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