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Name | Free fatty acid receptor 1 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Ffar1 |
Synonym | FFA1 receptor FFA1R G protein-coupled receptor 40 G-protein coupled receptor 40 GPR40 |
Disease | N/A for non-human GPCRs |
Length | 300 |
Amino acid sequence | MDLPPQLSFALYVSAFALGFPLNLLAIRGAVSHAKLRLTPSLVYTLHLGCSDLLLAITLPLKAVEALASGAWPLPLPFCPVFALAHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAIRRPRYSWGVCVAIWALVLCHLGLALGLETSGSWLDNSTSSLGINIPVNGSPVCLEAWDPDSARPARLSFSILLFFLPLVITAFCYVGCLRALVRSGLSHKRKLRAAWVAGGALLTLLLCLGPYNASNVASFINPDLGGSWRKLGLITGAWSVVLNPLVTGYLGTGPGRGTICVTRTQRGTIQK |
UniProt | Q76JU9 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5411 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CID 53248848 |
---|---|
Molecular formula | C21H14F5NO5 |
IUPAC name | 5-[1-[4-[2-(difluoromethoxy)-4-(trifluoromethyl)phenoxy]phenyl]but-2-ynyl]-1,3-oxazolidine-2,4-dione |
Molecular weight | 455.337 |
Hydrogen bond acceptor | 10 |
Hydrogen bond donor | 1 |
XlogP | 5.4 |
Synonyms | N/A |
Inchi Key | IEYUZLGWSIHESL-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C21H14F5NO5/c1-2-3-14(17-18(28)27-20(29)32-17)11-4-7-13(8-5-11)30-15-9-6-12(21(24,25)26)10-16(15)31-19(22)23/h4-10,14,17,19H,1H3,(H,27,28,29) |
PubChem CID | 53248848 |
ChEMBL | CHEMBL1777876 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 266.0 nM | PMID21514824 | ChEMBL |
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