Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only
Online Services

I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

You can:

GPCR

NameN-formyl peptide receptor 3
SpeciesHomo sapiens (Human)
GeneFPR3
SynonymFMLP-related receptor II
Lxa4r
LXA4-R
FPRL2
Fprl1
[ Show all ]
DiseaseN/A
Length353
Amino acid sequenceMETNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNFAFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPILYVFMGRNFQERLIRSLPTSLERALTEVPDSAQTSNTDTTSASPPEETELQAM
UniProtP25089
Protein Data BankN/A
GPCR-HGmod modelP25089
3D structure modelThis predicted structure model is from GPCR-EXP P25089.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLN/A
IUPHAR224
DrugBankN/A

Ligand

NameCHEMBL2391256
Molecular formulaC23H24BrN3O3
IUPAC nameN-(4-bromophenyl)-2-[5-[(3-methoxyphenyl)methyl]-6-oxo-3-propan-2-ylpyridazin-1-yl]acetamide
Molecular weight470.367
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP4.3
SynonymsBDBM50435937
Inchi KeyIJHCATOAXCRMJB-UHFFFAOYSA-N
Inchi IDInChI=1S/C23H24BrN3O3/c1-15(2)21-13-17(11-16-5-4-6-20(12-16)30-3)23(29)27(26-21)14-22(28)25-19-9-7-18(24)8-10-19/h4-10,12-13,15H,11,14H2,1-3H3,(H,25,28)
PubChem CID71698529
ChEMBLCHEMBL2391256
IUPHARN/A
BindingDB50435937
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
EC5017400.0 nMPMID23685570BindingDB

yangzhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218