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Name | D(1) dopamine receptor |
---|---|
Species | Carassius auratus (Goldfish) |
Gene | |
Synonym | Dopamine D1 receptor |
Disease | N/A for non-human GPCRs |
Length | 363 |
Amino acid sequence | MAVLDLNLTTVIDSGFMESDRSVRVLTGCFLSVLILSTLLGNTLVCAAVTKFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVTEVAGFWPFGAFCDIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPRVAFVMISGAWTLSVLISFIPVQLKWHKAQPIGFLEVNASRRDLPTDNCDSSLNRTYAISSSLISFYIPVAIMIVTYTQIYRIAQKQIRRISALERAAESAQIRHDSMGSGSNMDLESSFKLSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCKRTSNGLPCISPTTFDVFVWFGWANSSLNPIIYAFNADFRRAFAILLGCQRLCPGSISMETPSLNKN |
UniProt | P35406 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2368 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL542593 |
---|---|
Molecular formula | C15H16BrNO2S |
IUPAC name | (1S,10R)-16-thia-11-azatetracyclo[8.7.0.02,7.013,17]heptadeca-2,4,6,13(17),14-pentaene-4,5-diol;hydrobromide |
Molecular weight | 354.262 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 4 |
XlogP | None |
Synonyms | N/A |
Inchi Key | IJVRIRGMZPKDAM-GGMFNZDASA-N |
Inchi ID | InChI=1S/C15H15NO2S.BrH/c17-12-5-8-1-2-11-14(10(8)6-13(12)18)15-9(7-16-11)3-4-19-15;/h3-6,11,14,16-18H,1-2,7H2;1H/t11-,14+;/m1./s1 |
PubChem CID | 45259925 |
ChEMBL | CHEMBL542593 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 3200.0 nM | PMID9171869 | ChEMBL |
IA | 48.0 % | PMID9171869 | ChEMBL |
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