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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 1
Species	Meleagris gallopavo (Wild turkey)
Gene	P2RY1
Synonym	6H1 orphan receptor ADP receptor P2Y1 Purinergic receptor
Disease	N/A for non-human GPCRs
Length	362
Amino acid sequence	MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
UniProt	P49652
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5720
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL431649
Molecular formula	C11H16ClN5O8P2
IUPAC name	[2-[2-chloro-6-(methylamino)purin-9-yl]-1-(phosphonooxymethyl)cyclopropyl]methyl dihydrogen phosphate
Molecular weight	443.674
Hydrogen bond acceptor	12
Hydrogen bond donor	5
XlogP	-2.0
Synonyms	BDBM50104028 Phosphoric acid mono-[2-(2-chloro-6-methylamino-purin-9-yl)-1-phosphonooxymethyl-cyclopropylmethyl] ester 2-Chloro-9-[2,2-bis(phosphonooxymethyl)cyclopropyl]-N-methyl-9H-purine-6-amine
Inchi Key	IKGWLEDSKVGOTE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H16ClN5O8P2/c1-13-8-7-9(16-10(12)15-8)17(5-14-7)6-2-11(6,3-24-26(18,19)20)4-25-27(21,22)23/h5-6H,2-4H2,1H3,(H,13,15,16)(H2,18,19,20)(H2,21,22,23)
PubChem CID	10873926
ChEMBL	CHEMBL431649
IUPHAR	N/A
BindingDB	50104028
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Experimental Data

Parameter	Value	Reference	Database source
Activity	100.0 %	PMID11543678	ChEMBL
IC50	2360.0 nM	PMID11543678	BindingDB,ChEMBL

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