You can:
Name | Somatostatin receptor type 1 |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Sstr1 |
Synonym | SRIF-2 SS-1-R SS1-R SS1R SST1 receptor |
Disease | N/A for non-human GPCRs |
Length | 391 |
Amino acid sequence | MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCASRISTL |
UniProt | P28646 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4652 |
IUPHAR | 355 |
DrugBank | N/A |
Name | CHEMBL495264 |
---|---|
Molecular formula | C30H33ClF3N3O |
IUPAC name | 3-[2-(9H-fluoren-9-yl)ethyl-methylamino]-1-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propan-1-one;hydrochloride |
Molecular weight | 544.059 |
Hydrogen bond acceptor | 6 |
Hydrogen bond donor | 1 |
XlogP | None |
Synonyms | N/A |
Inchi Key | IPCPRINKGMTFTB-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C30H32F3N3O.ClH/c1-34(15-13-28-26-11-4-2-9-24(26)25-10-3-5-12-27(25)28)16-14-29(37)36-19-17-35(18-20-36)23-8-6-7-22(21-23)30(31,32)33;/h2-12,21,28H,13-20H2,1H3;1H |
PubChem CID | 44565007 |
ChEMBL | CHEMBL495264 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Kd | 61.66 nM | PMID19208473 | ChEMBL |
zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218