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Name | Galanin receptor type 2 |
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Species | Homo sapiens (Human) |
Gene | GALR2 |
Synonym | GAL2 receptor GAL2-R GALNR2 GALR-2 |
Disease | N/A |
Length | 387 |
Amino acid sequence | MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA |
UniProt | O43603 |
Protein Data Bank | N/A |
GPCR-HGmod model | O43603 |
3D structure model | This predicted structure model is from GPCR-EXP O43603. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3176 |
IUPHAR | 244 |
DrugBank | N/A |
Name | 2-(2,5-dinitrothiophen-3-yl)pyrimidine |
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Molecular formula | C8H4N4O4S |
IUPAC name | 2-(2,5-dinitrothiophen-3-yl)pyrimidine |
Molecular weight | 252.204 |
Hydrogen bond acceptor | 7 |
Hydrogen bond donor | 0 |
XlogP | 1.9 |
Synonyms | AI-942/13331097 SMR000226688 2-(2,5-dinitro-3-thiophenyl)pyrimidine CHEMBL1400481 MLS000700336 [ Show all ] |
Inchi Key | JHHSYNZURGGRBL-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C8H4N4O4S/c13-11(14)6-4-5(8(17-6)12(15)16)7-9-2-1-3-10-7/h1-4H |
PubChem CID | 3319616 |
ChEMBL | CHEMBL1400481 |
IUPHAR | N/A |
BindingDB | 34827 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 8959.0 nM | , PubChem BioAssay data set | BindingDB,ChEMBL |
IC50 | 9608.0 nM | , PubChem BioAssay data set | BindingDB,ChEMBL |
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