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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin D2 receptor
Species	Mus musculus (Mouse)
Gene	Ptgdr
Synonym	prostanoid DP receptor-like Prostanoid DP receptor prostaglandin D2 receptor (DP) PGD2 receptor PGD receptor DP1 receptor DP1 PTGDR1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	357
Amino acid sequence	MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGTWCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
UniProt	P70263
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3933
IUPHAR	338
DrugBank	N/A

Ligand

Name	CHEMBL361457
Molecular formula	C26H23NO4
IUPAC name	2-[2-methyl-1-[4-(2-phenylethoxy)benzoyl]indol-4-yl]acetic acid
Molecular weight	413.473
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.3
Synonyms	359582-76-6 [2-Methyl-1-(4-phenethyloxy-benzoyl)-1H-indol-4-yl]-acetic acid DTXSID50462134 1H-Indole-4-acetic acid, 2-methyl-1-[4-(2-phenylethoxy)benzoyl]- SCHEMBL4548356 BDBM50152513 CTK1B6593 [ Show all ]
Inchi Key	JLYOJYCKWIZTAQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H23NO4/c1-18-16-23-21(17-25(28)29)8-5-9-24(23)27(18)26(30)20-10-12-22(13-11-20)31-15-14-19-6-3-2-4-7-19/h2-13,16H,14-15,17H2,1H3,(H,28,29)
PubChem CID	11315933
ChEMBL	CHEMBL361457
IUPHAR	N/A
BindingDB	50152513
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	120.0 nM	PMID15341946	BindingDB,ChEMBL
Ki	1.8 nM	PMID15341946	BindingDB,ChEMBL

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