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Name | Galanin receptor type 2 |
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Species | Homo sapiens (Human) |
Gene | GALR2 |
Synonym | GAL2 receptor GAL2-R GALNR2 GALR-2 |
Disease | N/A |
Length | 387 |
Amino acid sequence | MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA |
UniProt | O43603 |
Protein Data Bank | N/A |
GPCR-HGmod model | O43603 |
3D structure model | This predicted structure model is from GPCR-EXP O43603. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3176 |
IUPHAR | 244 |
DrugBank | N/A |
Name | MLS000696629 |
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Molecular formula | C23H28N4O3S2 |
IUPAC name | N'-(4,6-dimethyl-1,3-benzothiazol-2-yl)-4-(3,5-dimethylpiperidin-1-yl)sulfonylbenzohydrazide |
Molecular weight | 472.622 |
Hydrogen bond acceptor | 7 |
Hydrogen bond donor | 2 |
XlogP | 5.5 |
Synonyms | HMS2244N24 N'-(4,6-dimethylbenzo[d]thiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzohydrazide BDBM41951 MolPort-003-038-516 cid_12006126 [ Show all ] |
Inchi Key | LZVBTZGFYLELRU-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C23H28N4O3S2/c1-14-10-17(4)21-20(11-14)31-23(24-21)26-25-22(28)18-5-7-19(8-6-18)32(29,30)27-12-15(2)9-16(3)13-27/h5-8,10-11,15-16H,9,12-13H2,1-4H3,(H,24,26)(H,25,28) |
PubChem CID | 12006126 |
ChEMBL | CHEMBL1383333 |
IUPHAR | N/A |
BindingDB | 41951 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | <55700.0 nM | , PubChem BioAssay data set | BindingDB,ChEMBL |
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