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Name | Galanin receptor type 2 |
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Species | Homo sapiens (Human) |
Gene | GALR2 |
Synonym | GAL2 receptor GAL2-R GALNR2 GALR-2 |
Disease | N/A |
Length | 387 |
Amino acid sequence | MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA |
UniProt | O43603 |
Protein Data Bank | N/A |
GPCR-HGmod model | O43603 |
3D structure model | This predicted structure model is from GPCR-EXP O43603. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3176 |
IUPHAR | 244 |
DrugBank | N/A |
Name | MLS000567024 |
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Molecular formula | C14H9N3S |
IUPAC name | (E)-2-(1H-benzimidazol-2-yl)-3-thiophen-2-ylprop-2-enenitrile |
Molecular weight | 251.307 |
Hydrogen bond acceptor | 3 |
Hydrogen bond donor | 1 |
XlogP | 3.0 |
Synonyms | 1H-Benzimidazole-2-acetonitrile, .alpha.-(2-thienylmethylene)- BDBM42055 (2E)-2-benzimidazol-2-yl-3-(2-thienyl)prop-2-enenitrile CHEMBL116569 SR-01000046927 [ Show all ] |
Inchi Key | MDVSLHGZTWHJMW-CSKARUKUSA-N |
Inchi ID | InChI=1S/C14H9N3S/c15-9-10(8-11-4-3-7-18-11)14-16-12-5-1-2-6-13(12)17-14/h1-8H,(H,16,17)/b10-8+ |
PubChem CID | 5334847 |
ChEMBL | CHEMBL116569 |
IUPHAR | N/A |
BindingDB | 42055 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | <42000.0 nM | , PubChem BioAssay data set | BindingDB,ChEMBL |
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