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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Leukotriene B4 receptor 2
Species	Homo sapiens (Human)
Gene	LTB4R2
Synonym	NOP9 12-HHT receptor Seven transmembrane receptor BLTR2 LTB4-R2 LTB4-R 2 LTB4 receptor JULF2 Leukotriene B4 receptor BLT2 BLTR2 BLT2 receptor [ Show all ]
Disease	Inflammatory bowel disease
Length	358
Amino acid sequence	MSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAAAHLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEARGGGRSREGTMELRTTPQLKVVGQGRGNGDPGGGMEKDGPEWDL
UniProt	Q9NPC1
Protein Data Bank	N/A
GPCR-HGmod model	Q9NPC1
3D structure model	This predicted structure model is from GPCR-EXP Q9NPC1.
BioLiP	N/A
Therapeutic Target Database	T30563
ChEMBL	CHEMBL3191
IUPHAR	268
DrugBank	BE0003489

Ligand

Name	6,8,11,14-Eicosatetraenoicacid, 5-oxo-
Molecular formula	C20H30O3
IUPAC name	5-oxoicosa-6,8,11,14-tetraenoic acid
Molecular weight	318.457
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.1
Synonyms	126432-17-5 Bio1_000638 KBio2_000173 6,8,11,14-Eicosatetraenoicacid, 5-oxo-, (6E,8Z,11Z,14Z)- Bio2_000653 KBio3_000345 ACMC-20m9rc CTK0H5493 KBioSS_000173 5-oxoicosa-6,8,11,14-tetraenoic acid Bio1_001127 KBio2_002741 AC1L1CC6 CBiol_001863 KBio3_000346 106154-18-1 Bio1_000149 FT-0642611 Bio2_000173 KBio2_005309 ACMC-20c9n1 CTK0H4063 KBioGR_000173 [ Show all ]
Inchi Key	MEASLHGILYBXFO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16H,2-5,8,11,15,17-18H2,1H3,(H,22,23)
PubChem CID	1831
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1000.0 nM	PMID11006272	PDSP

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