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Name | 5-hydroxytryptamine receptor 1D |
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Species | Sus scrofa (Pig) |
Gene | HTR1D |
Synonym | 5-HT-1D 5-HT1D Serotonin receptor 1D |
Disease | N/A for non-human GPCRs |
Length | 291 |
Amino acid sequence | AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV |
UniProt | P79400 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4105 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL37317 |
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Molecular formula | C13H15N5O |
IUPAC name | 5-[[3-(2-aminoethyl)-1H-indol-5-yl]methyl]-1,2,4-oxadiazol-3-amine |
Molecular weight | 257.297 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 3 |
XlogP | 1.2 |
Synonyms | BDBM50406753 SCHEMBL8785777 5-[(3-Amino-1,2,4-oxadiazol-5-yl)methyl]-1H-indole-3-(ethanamine) |
Inchi Key | MQYFTEBJWOVBLK-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C13H15N5O/c14-4-3-9-7-16-11-2-1-8(5-10(9)11)6-12-17-13(15)18-19-12/h1-2,5,7,16H,3-4,6,14H2,(H2,15,18) |
PubChem CID | 11777228 |
ChEMBL | CHEMBL37317 |
IUPHAR | N/A |
BindingDB | 50406753 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 19.95 nM | PMID8496922 | BindingDB,ChEMBL |
zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218