You can:
Name | Alpha-1A adrenergic receptor |
---|---|
Species | Oryctolagus cuniculus (Rabbit) |
Gene | ADRA1A |
Synonym | Alpha-1A adrenoceptor Alpha-1A adrenoreceptor Alpha-1C adrenergic receptor |
Disease | N/A for non-human GPCRs |
Length | 466 |
Amino acid sequence | MVFLSGNASDSSNCTHPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIISLCVISIDRYIGVSYPLRYPTIVTQRRGLRALLCVWAFSLVISVGPLFGWRQPAPDDETICQINEEPGYVLFSALGSFYVPLTIILAMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGVASAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPPETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLKIQCLRRKQSSKHALGYTLHAPSQALEGQHKDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPRGSARITVPKDQSACTTARVRSKSFLQVCCCVGPSTPNPGENHQVPTIKIHTISLSENGEEV |
UniProt | O02824 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3637 |
IUPHAR | N/A |
DrugBank | N/A |
Name | AC1NKXXY |
---|---|
Molecular formula | C17H19N3O |
IUPAC name | 3-[N-(4,5-dihydro-1H-imidazol-3-ium-2-ylmethyl)-4-methylanilino]phenolate |
Molecular weight | 281.359 |
Hydrogen bond acceptor | 2 |
Hydrogen bond donor | 2 |
XlogP | 3.3 |
Synonyms | STL054299 AKOS005707227 3-[(4,5-dihydro-1H-imidazol-3-ium-2-ylmethyl)(4-methylphenyl)amino]phenolate MCULE-3004652227 3-[N-(4,5-dihydro-1H-imidazol-3-ium-2-ylmethyl)-4-methylanilino]phenolate [ Show all ] |
Inchi Key | MRBDMNSDAVCSSF-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19) |
PubChem CID | 4920903 |
ChEMBL | CHEMBL597 |
IUPHAR | 502 |
BindingDB | 31046 |
DrugBank | DB00692 |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Kd | 6.31 nM | PMID9276013 | ChEMBL |
zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218