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Name | Somatostatin receptor type 1 |
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Species | Rattus norvegicus (Rat) |
Gene | Sstr1 |
Synonym | SRIF-2 SS-1-R SS1-R SS1R SST1 receptor |
Disease | N/A for non-human GPCRs |
Length | 391 |
Amino acid sequence | MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCASRISTL |
UniProt | P28646 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4652 |
IUPHAR | 355 |
DrugBank | N/A |
Name | CHEMBL491144 |
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Molecular formula | C29H35ClN4O2 |
IUPAC name | 6-[4-[3-[2-(9H-fluoren-9-yl)ethyl-methylamino]propanoyl]piperazin-1-yl]-1-methylpyridin-2-one;hydrochloride |
Molecular weight | 507.075 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 1 |
XlogP | None |
Synonyms | N/A |
Inchi Key | MVOHUCZVXSEBIN-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C29H34N4O2.ClH/c1-30(16-14-26-24-10-5-3-8-22(24)23-9-4-6-11-25(23)26)17-15-29(35)33-20-18-32(19-21-33)27-12-7-13-28(34)31(27)2;/h3-13,26H,14-21H2,1-2H3;1H |
PubChem CID | 44565063 |
ChEMBL | CHEMBL491144 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Kd | 2.138 nM | PMID19208473 | ChEMBL |
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