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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Growth hormone secretagogue receptor type 1
Species	Homo sapiens (Human)
Gene	GHSR
Synonym	ghrelin receptor GH-releasing peptide receptor GHRP GHS-R growth hormone-releasing peptide receptor ghrelin receptor 1a [ Show all ]
Disease	N/A
Length	366
Amino acid sequence	MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT
UniProt	Q92847
Protein Data Bank	N/A
GPCR-HGmod model	Q92847
3D structure model	This predicted structure model is from GPCR-EXP Q92847.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4616
IUPHAR	246
DrugBank	BE0003383

Ligand

Name	CHEMBL489402
Molecular formula	C20H22Cl2N2O2
IUPAC name	2-(3-chlorophenoxy)-N-(2-chlorophenyl)-N-[[(2R)-pyrrolidin-2-yl]methyl]propanamide
Molecular weight	393.308
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.8
Synonyms	BDBM50264487 2-(3-chlorophenoxy)-N-(2-chlorophenyl)-N-((R)-pyrrolidin-2-ylmethyl)propanamide
Inchi Key	BETBBRQIGQOQCK-BZSJEYESSA-N
Inchi ID	InChI=1S/C20H22Cl2N2O2/c1-14(26-17-8-4-6-15(21)12-17)20(25)24(13-16-7-5-11-23-16)19-10-3-2-9-18(19)22/h2-4,6,8-10,12,14,16,23H,5,7,11,13H2,1H3/t14?,16-/m1/s1
PubChem CID	44579881
ChEMBL	CHEMBL489402
IUPHAR	N/A
BindingDB	50264487
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Activity	70.0 %	PMID18722770	ChEMBL
EC50	780.0 nM	PMID18722770	BindingDB,ChEMBL

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