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Name | Mu-type opioid receptor |
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Species | Homo sapiens (Human) |
Gene | OPRM1 |
Synonym | hMOP M-OR-1 MOP opioid receptor, mu 1 opioid receptor [ Show all ] |
Disease | Diarrhea Inflammatory disease Pain Major depressive disorder Migraine [ Show all ] |
Length | 400 |
Amino acid sequence | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP |
UniProt | P35372 |
Protein Data Bank | N/A |
GPCR-HGmod model | P35372 |
3D structure model | This predicted structure model is from GPCR-EXP P35372. |
BioLiP | N/A |
Therapeutic Target Database | T47768 |
ChEMBL | CHEMBL233 |
IUPHAR | 319 |
DrugBank | BE0000770 |
Name | 1-(cyclohexylmethyl)pyrrolidine |
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Molecular formula | C11H21N |
IUPAC name | 1-(cyclohexylmethyl)pyrrolidine |
Molecular weight | 167.296 |
Hydrogen bond acceptor | 1 |
Hydrogen bond donor | 0 |
XlogP | 3.1 |
Synonyms | CTK1E5996 AC1L582T Pyrrolidine, 1-(cyclohexylmethyl)- 5005-27-6 DTXSID70276775 [ Show all ] |
Inchi Key | ADGIWWYGVBZYMC-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C11H21N/c1-2-6-11(7-3-1)10-12-8-4-5-9-12/h11H,1-10H2 |
PubChem CID | 199798 |
ChEMBL | CHEMBL2030634 |
IUPHAR | N/A |
BindingDB | 50384293 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Inhibition | >50.0 % | PMID22607684 | ChEMBL |
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