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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin F2-alpha receptor
Species	Mus musculus (Mouse)
Gene	Ptgfr
Synonym	prostaglandin F2-alpha receptor prostaglandin F receptor (FP) prostaglandin F receptor PGF2-alpha receptor PGF2 alpha receptor PGF receptor PF2AR FP receptor Prostanoid FP receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	366
Amino acid sequence	MSMNSSKQPVSPAAGLIANTTCQTENRLSVFFSIIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGGIAVFVYASDKDWIRFDQSNILCSIFGISMVFSGLCPLFLGSAMAIERCIGVTNPIFHSTKITSKHVKMILSGVCMFAVFVAVLPILGHRDYQIQASRTWCFYNTEHIEDWEDRFYLLFFSFLGLLALGVSFSCNAVTGVTLLRVKFRSQQHRQGRSHHLEMIIQLLAIMCVSCVCWSPFLVTMANIAINGNNSPVTCETTLFALRMATWNQILDPWVYILLRKAVLRNLYKLASRCCGVNIISLHIWELSSIKNSLKVAAISESPAAEKESQQASSEAGL
UniProt	P43117
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5000
IUPHAR	344
DrugBank	N/A

Ligand

Name	CHEMBL2325976
Molecular formula	C32H55N3O9S3
IUPAC name	(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-N-ethyl-N-[(4R)-2-(3-methoxypropyl)-1,1-dioxo-6-sulfamoyl-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazin-4-yl]hept-5-enamide
Molecular weight	721.984
Hydrogen bond acceptor	12
Hydrogen bond donor	4
XlogP	2.2
Synonyms	N/A
Inchi Key	PSMYZBYTIIQVMC-LNEVYKPISA-N
Inchi ID	InChI=1S/C32H55N3O9S3/c1-4-6-9-13-23(36)16-17-25-24(28(37)21-29(25)38)14-10-7-8-11-15-30(39)35(5-2)27-22-34(18-12-19-44-3)47(42,43)32-26(27)20-31(45-32)46(33,40)41/h7,10,16-17,20,23-29,32,36-38H,4-6,8-9,11-15,18-19,21-22H2,1-3H3,(H2,33,40,41)/b10-7-,17-16+/t23-,24+,25+,26?,27-,28-,29+,32?/m0/s1
PubChem CID	71552410
ChEMBL	CHEMBL2325976
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<5011.87 nM	PMID23317571	ChEMBL

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