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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neuromedin-K receptor
Species	Cavia porcellus (Guinea pig)
Gene	TACR3
Synonym	Neurokinin B receptor NK-3 receptor NK-3R NKR Tachykinin receptor 3
Disease	N/A for non-human GPCRs
Length	440
Amino acid sequence	MASPAGNLSAWPGWGWPPPAALRNLTSSPAPTASPSPAPSWTPSPRPGPAHPFLQPPWAVALWSLAYGAVVAVAVLGNLVVIWIVLAHKRMRTVTNSFLVNLAFADAAMAALNALVNFIYALHGEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATRIVIGSIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGSRQHFTYHMIVIVLVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYQEQLKAKRKVVKMMIIVVVTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIHVSSYDELELKATRLHPMRQSSLYTVTRMESMSVVFDSNDGDSARSSHQKRGTTRDVGSNVCSRRNSKSTSTTASFVSSSHMSVEEGS
UniProt	P30098
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3799
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL295680
Molecular formula	C20H20N2O2
IUPAC name	4-benzyl-2-(1H-indol-3-ylmethyl)morpholin-3-one
Molecular weight	320.392
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.0
Synonyms	BDBM50287926 4-Benzyl-2-(1H-indol-3-ylmethyl)-morpholin-3-one
Inchi Key	ROOCUTOICRZTPC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20N2O2/c23-20-19(12-16-13-21-18-9-5-4-8-17(16)18)24-11-10-22(20)14-15-6-2-1-3-7-15/h1-9,13,19,21H,10-12,14H2
PubChem CID	10245452
ChEMBL	CHEMBL295680
IUPHAR	N/A
BindingDB	50287926
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	>10.0 %	Bioorg. Med. Chem. Lett., (1996) 6:2:165	ChEMBL

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