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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	B1 bradykinin receptor
Species	Mus musculus (Mouse)
Gene	Bdkrb1
Synonym	bradykinin receptor BKR1 BK-1 receptor B1R B1BKR B1 receptor kinin B1 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	334
Amino acid sequence	MASQASLKLQPSNQSQQAPPNITSCEGAPEAWDLLCRVLPGFVITVCFFGLLGNLLVLSFFLLPWRRWWQQRRQRLTIAEIYLANLAASDLVFVLGLPFWAENVGNRFNWPFGSDLCRVVSGVIKANLFISIFLVVAISQDRYRLLVYPMTSWGNRRRRQAQVTCLLIWVAGGLLSTPTFLLRSVKVVPDLNISACILLFPHEAWHFVRMVELNVLGFLLPLAAILYFNFHILASLRGQKEASRTRCGGPKDSKTMGLILTLVASFLVCWAPYHFFAFLDFLVQVRVIQDCFWKELTDLGLQLANFFAFVNSCLNPLIYVFAGRLFKTRVLGTL
UniProt	Q61125
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1250407
IUPHAR	41
DrugBank	N/A

Ligand

Name	SCHEMBL4031279
Molecular formula	C24H30Cl2N4O3S
IUPAC name	5-[(2,4-dichloro-3-methylphenyl)sulfonyl-methylamino]-N-[[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]methyl]-N-methylpentanamide
Molecular weight	525.489
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.3
Synonyms	CHEMBL2087032
Inchi Key	RQDWOKKPAYLVLK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H30Cl2N4O3S/c1-17-20(25)11-12-21(23(17)26)34(32,33)30(3)15-5-4-6-22(31)29(2)16-18-7-9-19(10-8-18)24-27-13-14-28-24/h7-12H,4-6,13-16H2,1-3H3,(H,27,28)
PubChem CID	11541927
ChEMBL	CHEMBL2087032
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
pKb	6.0 -	PMID22369198	ChEMBL

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