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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	B1 bradykinin receptor
Species	Macaca fascicularis (Crab-eating macaque)
Gene	BDKRB1
Synonym	B1R BK-1 receptor
Disease	N/A for non-human GPCRs
Length	352
Amino acid sequence	MASWPPLQLQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICSFGLLGNLFVLLVFLLPRRRLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGIIKANLFISIFLVVAISQDRYCVLVHPMASRRRQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLPHEAWHFARIVELNILAFLLPLAAIIFFNYHILASLRGREEVSRTRCGGSKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFLAFTNSSLNPVIYVFAGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
UniProt	Q3BCU0
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5155
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL489203
Molecular formula	C29H30N6O2
IUPAC name	1-benzyl-N-[3-[[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]methyl-methylamino]-3-oxopropyl]benzimidazole-2-carboxamide
Molecular weight	494.599
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.5
Synonyms	BDBM50264446 N-(3-((4-(4,5-dihydro-1H-imidazol-2-yl)benzyl)(methyl)amino)-3-oxopropyl)-1-benzyl-1H-benzo[d]imidazole-2-carboxamide
Inchi Key	RTGZGGMIBCDDAZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H30N6O2/c1-34(19-22-11-13-23(14-12-22)27-30-17-18-31-27)26(36)15-16-32-29(37)28-33-24-9-5-6-10-25(24)35(28)20-21-7-3-2-4-8-21/h2-14H,15-20H2,1H3,(H,30,31)(H,32,37)
PubChem CID	44579865
ChEMBL	CHEMBL489203
IUPHAR	N/A
BindingDB	50264446
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	54.0 nM	PMID18752949	BindingDB,ChEMBL

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