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Name | B1 bradykinin receptor |
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Species | Rattus norvegicus (Rat) |
Gene | Bdkrb1 |
Synonym | KB1 bradykinin receptor BKR1 BK-1 receptor B1R [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 337 |
Amino acid sequence | MASEVLLELQPSNRSLQAPANITSCESALEDWDLLYRVLPGFVITICFFGLLGNLLVLSFFLLPWRQWWWQQRQRQQRLTIAEIYLANLAASDLVFVLGLPFWAENIGNRFNWPFGTDLCRVVSGVIKANLFVSIFLVVAISQDRYRLLVYPMTSWGYRRRRQAQATCLLIWVAGGLLSIPTFLLRSVKVVPDLNVSACILLFPHEAWHFARMVELNVLGFLLPVTAIIFFNYHILASLRGQKEASRTRCGGPKGSKTTGLILTLVASFLVCWCPYHFFAFLDFLVQVRVIQDCSWKEITDLGLQLANFFAFVNSCLNPLIYVFAGRLLKTRVLGTL |
UniProt | P97583 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4613 |
IUPHAR | 41 |
DrugBank | N/A |
Name | CHEMBL329578 |
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Molecular formula | C43H70N12O10 |
IUPAC name | (2S)-2-[[(2S)-1-[(2S)-2-[[2-[[1-[[2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]cyclononanecarbonyl]amino]acetyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid |
Molecular weight | 915.107 |
Hydrogen bond acceptor | 13 |
Hydrogen bond donor | 12 |
XlogP | -3.3 |
Synonyms | N/A |
Inchi Key | UDARTKBKIWLIDD-ZTTXAYQISA-N |
Inchi ID | InChI=1S/C43H70N12O10/c44-21-11-8-16-29(45)36(59)52-30(17-12-22-48-42(46)47)37(60)49-26-35(58)54-43(19-9-3-1-2-4-10-20-43)41(65)50-25-34(57)51-32(27-56)39(62)55-23-13-18-33(55)38(61)53-31(40(63)64)24-28-14-6-5-7-15-28/h5-7,14-15,29-33,56H,1-4,8-13,16-27,44-45H2,(H,49,60)(H,50,65)(H,51,57)(H,52,59)(H,53,61)(H,54,58)(H,63,64)(H4,46,47,48)/t29-,30-,31-,32-,33-/m0/s1 |
PubChem CID | 10533789 |
ChEMBL | CHEMBL329578 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
pD2 | 5.4 - | PMID11170638 | ChEMBL |
zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218