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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(2) dopamine receptor
Species	Canis lupus familiaris (Dog)
Gene	DRD2
Synonym	Dopamine D2 receptor
Disease	N/A for non-human GPCRs
Length	443
Amino acid sequence	MDPLNLSWYDDDLESQNWSRPFNGSEGKPGKPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTERSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTADSPAKPEKNGHAKDHPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCECNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
UniProt	Q9GJU1
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2703
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL41706
Molecular formula	C21H26ClN3O3
IUPAC name	4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-phenacyloxybenzamide
Molecular weight	403.907
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.0
Synonyms	4-Amino-2-(2-phenyl-2-oxoethoxy)-5-chloro-N-[2-(diethylamino)ethyl]benzamid BDBM50023819 SCHEMBL9777121 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-oxo-2-phenyl-ethoxy)-benzamide UFPUUPPDXVYKPL-UHFFFAOYSA-N
Inchi Key	UFPUUPPDXVYKPL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H26ClN3O3/c1-3-25(4-2)11-10-24-21(27)16-12-17(22)18(23)13-20(16)28-14-19(26)15-8-6-5-7-9-15/h5-9,12-13H,3-4,10-11,14,23H2,1-2H3,(H,24,27)
PubChem CID	14116890
ChEMBL	CHEMBL41706
IUPHAR	N/A
BindingDB	50023819
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
ED50	<3.0 mg.kg-1	PMID3397992	ChEMBL

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