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Name | Alpha-1A adrenergic receptor |
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Species | Oryctolagus cuniculus (Rabbit) |
Gene | ADRA1A |
Synonym | Alpha-1A adrenoceptor Alpha-1A adrenoreceptor Alpha-1C adrenergic receptor |
Disease | N/A for non-human GPCRs |
Length | 466 |
Amino acid sequence | MVFLSGNASDSSNCTHPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIISLCVISIDRYIGVSYPLRYPTIVTQRRGLRALLCVWAFSLVISVGPLFGWRQPAPDDETICQINEEPGYVLFSALGSFYVPLTIILAMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGVASAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPPETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLKIQCLRRKQSSKHALGYTLHAPSQALEGQHKDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPRGSARITVPKDQSACTTARVRSKSFLQVCCCVGPSTPNPGENHQVPTIKIHTISLSENGEEV |
UniProt | O02824 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3637 |
IUPHAR | N/A |
DrugBank | N/A |
Name | LASSBio-682 |
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Molecular formula | C19H22Cl2N2O2 |
IUPAC name | 1-[2-(1,3-benzodioxol-5-yl)ethyl]-4-(4-chlorophenyl)piperazine;hydrochloride |
Molecular weight | 381.297 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 1 |
XlogP | None |
Synonyms | CHEMBL2153426 |
Inchi Key | UZDCRAOBOSJCEU-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C19H21ClN2O2.ClH/c20-16-2-4-17(5-3-16)22-11-9-21(10-12-22)8-7-15-1-6-18-19(13-15)24-14-23-18;/h1-6,13H,7-12,14H2;1H |
PubChem CID | 53329790 |
ChEMBL | CHEMBL2153426 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Kb | 1240.0 nM | PMID21549456 | ChEMBL |
zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218