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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Free fatty acid receptor 1
Species	Mus musculus (Mouse)
Gene	Ffar1
Synonym	FFA1 receptor FFA1R G protein-coupled receptor 40 G-protein coupled receptor 40 GPR40
Disease	N/A for non-human GPCRs
Length	300
Amino acid sequence	MDLPPQLSFALYVSAFALGFPLNLLAIRGAVSHAKLRLTPSLVYTLHLGCSDLLLAITLPLKAVEALASGAWPLPLPFCPVFALAHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAIRRPRYSWGVCVAIWALVLCHLGLALGLETSGSWLDNSTSSLGINIPVNGSPVCLEAWDPDSARPARLSFSILLFFLPLVITAFCYVGCLRALVRSGLSHKRKLRAAWVAGGALLTLLLCLGPYNASNVASFINPDLGGSWRKLGLITGAWSVVLNPLVTGYLGTGPGRGTICVTRTQRGTIQK
UniProt	Q76JU9
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5411
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL1777863
Molecular formula	C19H14BrNO3
IUPAC name	3-[4-(2-bromo-4-cyanophenoxy)phenyl]hex-4-ynoic acid
Molecular weight	384.229
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.2
Synonyms	rac-3-(4-(2-bromo-4-cyanophenoxy)phenyl)hex-4-ynoic acid BDBM50344070
Inchi Key	VIXBOSFBBFQKIJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H14BrNO3/c1-2-3-15(11-19(22)23)14-5-7-16(8-6-14)24-18-9-4-13(12-21)10-17(18)20/h4-10,15H,11H2,1H3,(H,22,23)
PubChem CID	54582628
ChEMBL	CHEMBL1777863
IUPHAR	N/A
BindingDB	50344070
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	88.0 nM	PMID21514824	BindingDB,ChEMBL

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