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GPCR

NameGalanin receptor type 3
SpeciesRattus norvegicus (Rat)
GeneGalr3
SynonymGAL3 receptor
GAL3-R
Galnr3
GALR-3
GALR3
DiseaseN/A for non-human GPCRs
Length370
Amino acid sequenceMADIQNISLDSPGSVGAVAVPVIFALIFLLGMVGNGLVLAVLLQPGPSAWQEPRSTTDLFILNLAVADLCFILCCVPFQAAIYTLDAWLFGAFVCKTVHLLIYLTMYASSFTLAAVSLDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLCFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYSLASRHFRARFRRLWPCGRRRHRHHHRAHRALRRVQPASSGPAGYPGDARPRGWSMEPRGDALRGGGETRLTLSPRGPQ
UniProtO88626
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLN/A
IUPHARN/A
DrugBankN/A

Ligand

NameGalantide (M15)
Molecular formulaC23H30N2O3
IUPAC nameN-(2-methoxyphenyl)-N-[2-(4-methylphenoxy)ethyl]-2-piperidin-1-ylacetamide
Molecular weight382.504
Hydrogen bond acceptor4
Hydrogen bond donor0
XlogP4.2
SynonymsAC1MIFFU
BDBM85073
N-(2-methoxyphenyl)-N-[2-(4-methylphenoxy)ethyl]-2-piperidin-1-ylacetamide
CAS_3043476
NSC_3043476
Inchi KeyVQUPYGXNBXITAA-UHFFFAOYSA-N
Inchi IDInChI=1S/C23H30N2O3/c1-19-10-12-20(13-11-19)28-17-16-25(21-8-4-5-9-22(21)27-2)23(26)18-24-14-6-3-7-15-24/h4-5,8-13H,3,6-7,14-18H2,1-2H3
PubChem CID3043477
ChEMBLN/A
IUPHARN/A
BindingDB85073
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
Ki10.47 nMPMID9722565BindingDB

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