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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Melanocortin receptor 5
Species	Mus musculus (Mouse)
Gene	Mc5r
Synonym	MC5 receptor MC5-R MC5R melanocortin receptor 5
Disease	N/A for non-human GPCRs
Length	325
Amino acid sequence	MNSSSTLTVLNLTLNASEDGILGSNVKNKSLACEEMGIAVEVFLTLGLVSLLENILVIGAIVKNKNLHSPMYFFVGSLAVADMLVSMSNAWETVTIYLLNNKHLVIADTFVRHIDNVFDSMICISVVASMCSLLAIAVDRYITIFYALRYHHIMTARRSGVIIACIWTFCISCGIVFIIYYESKYVIICLISMFFTMLFFMVSLYIHMFLLARNHVKRIAASPRYNSVRQRTSMKGAITLTMLLGIFIVCWSPFFLHLILMISCPQNVYCSCFMSYFNMYLILIMCNSVIDPLIYALRSQEMRRTFKEIVCCHGFRRPCRLLGGY
UniProt	P41149
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4489
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL270691
Molecular formula	C27H21ClN2O2
IUPAC name	3-benzyl-8-chloro-1-(naphthalen-2-ylmethyl)-3,4-dihydro-1,4-benzodiazepine-2,5-dione
Molecular weight	440.927
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.7
Synonyms	BDBM50374115
Inchi Key	BZDRLTZGNVDUFJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H21ClN2O2/c28-22-12-13-23-25(16-22)30(17-19-10-11-20-8-4-5-9-21(20)14-19)27(32)24(29-26(23)31)15-18-6-2-1-3-7-18/h1-14,16,24H,15,17H2,(H,29,31)
PubChem CID	44457002
ChEMBL	CHEMBL270691
IUPHAR	N/A
BindingDB	50374115
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	4350.0 nM	PMID18271518	BindingDB,ChEMBL

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