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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Free fatty acid receptor 1
Species	Rattus norvegicus (Rat)
Gene	Ffar1
Synonym	FFA1 receptor FFA1R G protein-coupled receptor 40 G-protein coupled receptor 40 GPR40
Disease	N/A for non-human GPCRs
Length	300
Amino acid sequence	MDLPPQLSFALYVSAFALGFPLNLLAIRGAVSHAKLRLTPSLVYTLHLACSDLLLAITLPLKAVEALASGVWPLPLPFCPVFALAHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAIRRPCYSWGVCVAIWALVLCHLGLALGLEAPRGWVDNTTSSLGINIPVNGSPVCLEAWDPDSARPARLSFSILLFFLPLVITAFCYVGCLRALVHSGLSHKRKLRAAWVAGGALLTLLLCLGPYNASNVASFINPDLEGSWRKLGLITGAWSVVLNPLVTGYLGTGPGQGTICVTRTPRGTIQK
UniProt	Q8K3T4
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1795180
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3288350
Molecular formula	C22H22N2O3
IUPAC name	3-[2-[[3-(2,6-dimethylphenyl)phenyl]methoxy]pyrimidin-5-yl]propanoic acid
Molecular weight	362.429
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.1
Synonyms	BDBM50019089
Inchi Key	BZEUQTZFFNFICD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H22N2O3/c1-15-5-3-6-16(2)21(15)19-8-4-7-17(11-19)14-27-22-23-12-18(13-24-22)9-10-20(25)26/h3-8,11-13H,9-10,14H2,1-2H3,(H,25,26)
PubChem CID	90644292
ChEMBL	CHEMBL3288350
IUPHAR	N/A
BindingDB	50019089
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	1400.0 nM	PMID24835985	BindingDB,ChEMBL

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