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Name | Adenosine receptor A1 |
---|---|
Species | Gallus gallus (Chicken) |
Gene | ADORA1 |
Synonym | N/A |
Disease | N/A for non-human GPCRs |
Length | 324 |
Amino acid sequence | MAQSVTAFQAAYISIEVLIALVSVPGNILVIWAVKMNQALRDATFCFIVSLAVADVAVGALVIPLAIIINIGPQTEFYSCLMMACPVLILTESSILALLAIAVDRYLRVKIPVRYKSVVTPRRAAVAIACCWIVSFLVGLTPMFGWNNLNKVLGTRDLNVSHSEFVIKCQFETVISMEYMVYFNFFVWVLPPLLLMLLIYLEVFNLIRTQLNKKVSSSSNDPQKYYGKELKIAKSLALVLFLFALSWLPLHILNCITLFCPSCKTPHILTYIAIFLTHGNSAMNPIVYAFRIKKFRTAFLQIWNQYFCCKTNKSSSSSTAETVN |
UniProt | P49892 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2114 |
IUPHAR | N/A |
DrugBank | N/A |
Name | BDBM85775 |
---|---|
Molecular formula | C26H27NO4 |
IUPAC name | diethyl 2-methyl-6-phenyl-4-[(E)-2-phenylethenyl]-3,4-dihydropyridine-3,5-dicarboxylate |
Molecular weight | 417.505 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 0 |
XlogP | 4.7 |
Synonyms | N/A |
Inchi Key | VYXYBKWIYQGIEA-WUKNDPDISA-N |
Inchi ID | InChI=1S/C26H27NO4/c1-4-30-25(28)22-18(3)27-24(20-14-10-7-11-15-20)23(26(29)31-5-2)21(22)17-16-19-12-8-6-9-13-19/h6-17,21-22H,4-5H2,1-3H3/b17-16+ |
PubChem CID | 91898990 |
ChEMBL | N/A |
IUPHAR | N/A |
BindingDB | 85775 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 3425.4 nM | PMID11191840 | BindingDB |
zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218