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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Bos taurus (Bovine)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	Q95136
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2967
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL165022
Molecular formula	C17H25N
IUPAC name	4-penta-1,4-diyn-3-ylidene-N,N-dipropylcyclohexan-1-amine
Molecular weight	243.394
Hydrogen bond acceptor	1
Hydrogen bond donor	0
XlogP	4.2
Synonyms	[4-(1-Ethynyl-prop-2-ynylidene)-cyclohexyl]-dipropyl-amine BDBM50085336 ZINC13805529
Inchi Key	CFCGTXOJJUJIIE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H25N/c1-5-13-18(14-6-2)17-11-9-16(10-12-17)15(7-3)8-4/h3-4,17H,5-6,9-14H2,1-2H3
PubChem CID	10824155
ChEMBL	CHEMBL165022
IUPHAR	N/A
BindingDB	50085336
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	16000.0 nM	PMID10691700	BindingDB,ChEMBL

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