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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neuropeptide Y receptor type 5
Species	Mus musculus (Mouse)
Gene	Npy5r
Synonym	food intake receptor neuropeptide Y receptor type 5 NPY-Y5 receptor NPY5-R NPYY5-R Y5 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	466
Amino acid sequence	MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVKPEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
UniProt	O70342
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3802
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL2159172
Molecular formula	C20H23N3O4S
IUPAC name	4-(6-ethylsulfonyl-1H-benzimidazol-2-yl)-2-(4-methoxyphenyl)morpholine
Molecular weight	401.481
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.7
Synonyms	BDBM50394229
Inchi Key	CGHSLKDGCJGJRD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H23N3O4S/c1-3-28(24,25)16-8-9-17-18(12-16)22-20(21-17)23-10-11-27-19(13-23)14-4-6-15(26-2)7-5-14/h4-9,12,19H,3,10-11,13H2,1-2H3,(H,21,22)
PubChem CID	71458606
ChEMBL	CHEMBL2159172
IUPHAR	N/A
BindingDB	50394229
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	3.03 nM	PMID23025998	BindingDB,ChEMBL

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