You can:
Name | 5-hydroxytryptamine receptor 5A |
---|---|
Species | Mus musculus (Mouse) |
Gene | Htr5a |
Synonym | MR22 Htr5 5HT5- 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 5-HT5alpha [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 357 |
Amino acid sequence | MDLPVNLTSFSLSTPSSLEPNRSLDTEVLRPSRPFLSAFRVLVLTLLGFLAAATFTWNLLVLATILKVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRTRKRVSNVMILLTWALSTVISLAPLLFGWGETYSEPSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYRAAKFRMGSRKTNSVSPVPEAVEVKNATQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFPFFVTELISPLCSWDVPAIWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ |
UniProt | P30966 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3597 |
IUPHAR | 10 |
DrugBank | N/A |
Name | D-Lysergic acid |
---|---|
Molecular formula | C16H16N2O2 |
IUPAC name | 7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxylic acid |
Molecular weight | 268.316 |
Hydrogen bond acceptor | 3 |
Hydrogen bond donor | 2 |
XlogP | 0.0 |
Synonyms | lysergate 6-Methyl-9,10-didehydroergoline-8-carboxylic acid CAS_82-58-6 SureCN1162252 (+)-Lysergic acid [ Show all ] |
Inchi Key | ZAGRKAFMISFKIO-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C16H16N2O2/c1-18-8-10(16(19)20)5-12-11-3-2-4-13-15(11)9(7-17-13)6-14(12)18/h2-5,7,10,14,17H,6,8H2,1H3,(H,19,20) |
PubChem CID | 622688 |
ChEMBL | N/A |
IUPHAR | N/A |
BindingDB | 82080 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 2000.0 nM | PMID8549774 | BindingDB |
zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218