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Name | N-formyl peptide receptor 2 |
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Species | Homo sapiens (Human) |
Gene | FPR2 |
Synonym | FPRH1 FPRH2 FPRL1 HM63 Lipoxin A4 receptor [ Show all ] |
Disease | N/A |
Length | 351 |
Amino acid sequence | METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM |
UniProt | P25090 |
Protein Data Bank | N/A |
GPCR-HGmod model | P25090 |
3D structure model | This predicted structure model is from GPCR-EXP P25090. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4227 |
IUPHAR | 223 |
DrugBank | N/A |
Name | UNM000003539401 |
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Molecular formula | C23H15F3O7 |
IUPAC name | [3-(3,4-dimethoxyphenyl)-4-oxo-2-(trifluoromethyl)chromen-7-yl] furan-2-carboxylate |
Molecular weight | 460.361 |
Hydrogen bond acceptor | 10 |
Hydrogen bond donor | 0 |
XlogP | 4.8 |
Synonyms | [3-(3,4-dimethoxyphenyl)-4-oxo-2-(trifluoromethyl)chromen-7-yl] furan-2-carboxylate 3-(3,4-dimethoxyphenyl)-4-oxo-2-(trifluoromethyl)chromen-7-yl furan-2-carboxyl ate CCG-108739 MolPort-000-660-922 ST50184123 [ Show all ] |
Inchi Key | AFRGGYNZKHADNN-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C23H15F3O7/c1-29-15-8-5-12(10-18(15)30-2)19-20(27)14-7-6-13(32-22(28)16-4-3-9-31-16)11-17(14)33-21(19)23(24,25)26/h3-11H,1-2H3 |
PubChem CID | 1036463 |
ChEMBL | CHEMBL1473100 |
IUPHAR | N/A |
BindingDB | 40413 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | <66700.0 nM | N/A | BindingDB |
Ki | <40300.0 nM | N/A | BindingDB |
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