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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-C chemokine receptor type 3
Species	Rattus norvegicus (Rat)
Gene	Ccr3
Synonym	CKR3 chemokine (C-C motif) receptor 3 CD193 CCR3 CCR-3 CC-CKR-3 CC CKR3 C-C CKR-3 MIP-1alphaRL-2 (mouse) [ Show all ]
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MASNEEELKTVVETFETTPYEYEWAPPCEKVSIRELGSWLLPPLYSLVFIVGLLGNMMVVLILIKYRKLQIMTNIYLLNLAISDLLFLFTVPFWIHYVLWNEWGFGHCMCKMLSGLYYLALYSEIFFIILLTIDRYLAIVHAVLALRARTVTFATITSIITWGFAVLAALPEFIFHESQDNFGDLSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIQLIFVVMIVFFIFWTPYNLVLLLSAFHSTFLETSCQQSIHLDLAMQVTEVITHTHCCINPIIYAFVGERFRKHLRLFFHRNVAIYLRKYISFLPGEKLERTSSVSPSTGEQEISVVF
UniProt	O54814
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3928
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3355955
Molecular formula	C32H34F2N2O2S
IUPAC name	4-[[2-ethyl-6-fluoro-3-[1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-yl]indol-1-yl]methyl]benzoic acid
Molecular weight	548.693
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.0
Synonyms	BDBM50041194
Inchi Key	ZQJAWBVNTLAXOW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H34F2N2O2S/c1-2-29-31(23-14-17-35(18-15-23)16-3-19-39-27-11-8-25(33)9-12-27)28-13-10-26(34)20-30(28)36(29)21-22-4-6-24(7-5-22)32(37)38/h4-13,20,23H,2-3,14-19,21H2,1H3,(H,37,38)
PubChem CID	118721201
ChEMBL	CHEMBL3355955
IUPHAR	N/A
BindingDB	50041194
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Ki	2600.0 nM	PMID25497216	BindingDB,ChEMBL

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