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GPCR

NameG-protein coupled receptor 183
SpeciesHomo sapiens (Human)
GeneGPR183
SynonymEBI2 {ECO:0000303|PubMed:8383238}
lymphocyte-specific G protein-coupled receptor
hEBI2 {ECO:0000303|PubMed:22875855}
GPR183
G protein-coupled receptor 183
[ Show all ]
DiseaseN/A
Length361
Amino acid sequenceMDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNGK
UniProtP32249
Protein Data BankN/A
GPCR-HGmod modelP32249
3D structure modelThis predicted structure model is from GPCR-EXP P32249.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3259470
IUPHAR81
DrugBankN/A

Ligand

NameCHEMBL3560195
Molecular formulaC20H20BBrN2O4
IUPAC name[3-[4-[(E)-3-(4-bromophenyl)prop-2-enoyl]piperazine-1-carbonyl]phenyl]boronic acid
Molecular weight443.104
Hydrogen bond acceptor4
Hydrogen bond donor2
XlogPNone
SynonymsMLS-0472883.0001
Inchi KeyIILLKBXSLNSZHT-RMKNXTFCSA-N
Inchi IDInChI=1S/C20H20BBrN2O4/c22-18-7-4-15(5-8-18)6-9-19(25)23-10-12-24(13-11-23)20(26)16-2-1-3-17(14-16)21(27)28/h1-9,14,27-28H,10-13H2/b9-6+
PubChem CID73330412
ChEMBLCHEMBL3560195
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessPartition coefficient log P of this ligand is not available.

Experimental Data

ParameterValueReferenceDatabase source
IC5028.7 nMPubChem BioAssay data setChEMBL

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