You can:
Name | Somatostatin receptor type 1 |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Sstr1 |
Synonym | SRIF-2 SS-1-R SS1-R SS1R SST1 receptor |
Disease | N/A for non-human GPCRs |
Length | 391 |
Amino acid sequence | MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCASRISTL |
UniProt | P28646 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4652 |
IUPHAR | 355 |
DrugBank | N/A |
Name | CHEMBL252002 |
---|---|
Molecular formula | C24H26BrN5O |
IUPAC name | [(6aR,9R,10aR)-5-bromo-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]-(4-pyridin-2-ylpiperazin-1-yl)methanone |
Molecular weight | 480.41 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 2 |
XlogP | 3.2 |
Synonyms | BDBM50423469 |
Inchi Key | CQQQBUCNFNYLGF-WRWLIDTKSA-N |
Inchi ID | InChI=1S/C24H26BrN5O/c25-23-18-13-20-17(16-4-3-5-19(28-23)22(16)18)12-15(14-27-20)24(31)30-10-8-29(9-11-30)21-6-1-2-7-26-21/h1-7,15,17,20,27-28H,8-14H2/t15-,17-,20-/m1/s1 |
PubChem CID | 44447026 |
ChEMBL | CHEMBL252002 |
IUPHAR | N/A |
BindingDB | 50423469 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Kd | 169.82 nM | PMID18162395 | ChEMBL |
Kd | 170.0 nM | PMID18162395 | BindingDB |
zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218