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GPCR

NameCannabinoid receptor 2
SpeciesMus musculus (Mouse)
GeneCnr2
SynonymPeripheral cannabinoid receptor
mCB2
CB2-R
CB2 receptor
CB2
[ Show all ]
DiseaseN/A for non-human GPCRs
Length347
Amino acid sequenceMEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
UniProtP47936
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5373
IUPHAR57
DrugBankN/A

Ligand

Name(2E,4E)-N-isobutyltetradeca-2,4-dienamide
Molecular formulaC18H33NO
IUPAC name(2E,4E)-N-(2-methylpropyl)tetradeca-2,4-dienamide
Molecular weight279.468
Hydrogen bond acceptor1
Hydrogen bond donor1
XlogP6.6
Synonyms2,4-Tetradecadienamide, N-(2-methylpropyl)-, (2E,4E)-
N-Isobutyl-(2E,4E)-tetradeca-2,4-dienamide
AGJAUFUNZWHLKE-SQIWNDBBSA-N
N-(2-Methylpropyl)-2,4-tetradecadienamide
2,4-Tetradecadienamide, N-(2-methylpropyl)-, (E,E)-
[ Show all ]
Inchi KeyAGJAUFUNZWHLKE-SQIWNDBBSA-N
Inchi IDInChI=1S/C18H33NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-18(20)19-16-17(2)3/h12-15,17H,4-11,16H2,1-3H3,(H,19,20)/b13-12+,15-14+
PubChem CID10731388
ChEMBLCHEMBL2442640
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Experimental Data

ParameterValueReferenceDatabase source
Ki1170.0 nMPMID24095014ChEMBL

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