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Name | Taste receptor type 2 member 8 |
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Species | Homo sapiens (Human) |
Gene | TAS2R8 |
Synonym | T2R8 TAS2R8 Taste receptor family B member 5 taste receptor, type 2, member 8 TRB5 |
Disease | N/A |
Length | 309 |
Amino acid sequence | MFSPADNIFIILITGEFILGILGNGYIALVNWIDWIKKKKISTVDYILTNLVIARICLISVMVVNGIVIVLNPDVYTKNKQQIVIFTFWTFANYLNMWITTCLNVFYFLKIASSSHPLFLWLKWKIDMVVHWILLGCFAISLLVSLIAAIVLSCDYRFHAIAKHKRNITEMFHVSKIPYFEPLTLFNLFAIVPFIVSLISFFLLVRSLWRHTKQIKLYATGSRDPSTEVHVRAIKTMTSFIFFFFLYYISSILMTFSYLMTKYKLAVEFGEIAAILYPLGHSLILIVLNNKLRQTFVRMLTCRKIACMI |
UniProt | Q9NYW2 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9NYW2 |
3D structure model | This predicted structure model is from GPCR-EXP Q9NYW2. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3988599 |
IUPHAR | N/A |
DrugBank | N/A |
Name | SCHEMBL1615834 |
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Molecular formula | C19H22N4O4 |
IUPAC name | 2-(3,4-dimethoxyphenyl)-N-[1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]pyrazol-4-yl]acetamide |
Molecular weight | 370.409 |
Hydrogen bond acceptor | 6 |
Hydrogen bond donor | 1 |
XlogP | 1.8 |
Synonyms | US9247759, 4-34 CHEMBL3955012 BDBM210999 |
Inchi Key | BJNHEAMDRAPFMJ-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C19H22N4O4/c1-12-16(13(2)27-22-12)11-23-10-15(9-20-23)21-19(24)8-14-5-6-17(25-3)18(7-14)26-4/h5-7,9-10H,8,11H2,1-4H3,(H,21,24) |
PubChem CID | 57944941 |
ChEMBL | CHEMBL3955012 |
IUPHAR | N/A |
BindingDB | 210999 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 1110.0 nM | N/A | BindingDB |
IC50 | 1110.0 nM | None | ChEMBL |
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