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Name | Taste receptor type 2 member 14 |
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Species | Homo sapiens (Human) |
Gene | TAS2R14 |
Synonym | T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1 |
Disease | N/A |
Length | 317 |
Amino acid sequence | MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS |
UniProt | Q9NYV8 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9NYV8 |
3D structure model | This predicted structure model is from GPCR-EXP Q9NYV8. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3309105 |
IUPHAR | N/A |
DrugBank | N/A |
Name | SCHEMBL1278727 |
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Molecular formula | C23H23NO6S |
IUPAC name | 4-[(3-methoxyphenyl)methyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acid |
Molecular weight | 441.498 |
Hydrogen bond acceptor | 7 |
Hydrogen bond donor | 1 |
XlogP | 3.5 |
Synonyms | 4-(N-(3-methoxybenzyl)-N-(4-methoxybenzyl)sulfamoyl)-benzoic acid CHEMBL3931168 US9247759, 5-34 BDBM211112 PBUSWPKWYSFCLW-UHFFFAOYSA-N |
Inchi Key | PBUSWPKWYSFCLW-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C23H23NO6S/c1-29-20-10-6-17(7-11-20)15-24(16-18-4-3-5-21(14-18)30-2)31(27,28)22-12-8-19(9-13-22)23(25)26/h3-14H,15-16H2,1-2H3,(H,25,26) |
PubChem CID | 25207618 |
ChEMBL | CHEMBL3931168 |
IUPHAR | N/A |
BindingDB | 211112 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 2460.0 nM | None | ChEMBL |
IC50 | 2460.0 nM | N/A | BindingDB |
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