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Name | Taste receptor type 2 member 14 |
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Species | Homo sapiens (Human) |
Gene | TAS2R14 |
Synonym | T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1 |
Disease | N/A |
Length | 317 |
Amino acid sequence | MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS |
UniProt | Q9NYV8 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9NYV8 |
3D structure model | This predicted structure model is from GPCR-EXP Q9NYV8. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3309105 |
IUPHAR | N/A |
DrugBank | N/A |
Name | SCHEMBL1279324 |
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Molecular formula | C21H18ClNO4S |
IUPAC name | 4-[benzyl-[(4-chlorophenyl)methyl]sulfamoyl]benzoic acid |
Molecular weight | 415.888 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 1 |
XlogP | 4.2 |
Synonyms | US9247759, 5-137 CHEMBL3893065 US9247759, 5-77 BDBM211143 |
Inchi Key | QWHLUCMKDMXEJW-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C21H18ClNO4S/c22-19-10-6-17(7-11-19)15-23(14-16-4-2-1-3-5-16)28(26,27)20-12-8-18(9-13-20)21(24)25/h1-13H,14-15H2,(H,24,25) |
PubChem CID | 57422370 |
ChEMBL | CHEMBL3893065 |
IUPHAR | N/A |
BindingDB | 211143 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 3977.0 nM | None | ChEMBL |
IC50 | 3977.0 nM | N/A | BindingDB |
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