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Name | Mas-related G-protein coupled receptor member X2 |
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Species | Macaca mulatta (Rhesus macaque) |
Gene | MRGPRX2 |
Synonym | N/A |
Disease | N/A for non-human GPCRs |
Length | 329 |
Amino acid sequence | MDPTTPAWGTESTTMNGNDQALPLLCGKETMISVFLILFIALVGLVGNAFVLWLLGFRMRRNAFSVYVLSLAGADFLFLCFQMTSCLAYLINFFGSISINIPSFFTVMTCAYLAGLSMLSAISTERCLSVLWPIWYRCRRPRHLSAVMCVLLWALSLLLSILEGKFCGFLFSDDDPGWCQTFDFITAAWLMFLFVVLCGSSLALLVRILCGSRSLPLTRLYLTILLTVLIFLLCGLPFGIQWFLILWIWKNSVVLFCHIHPISVVLSSFNSSANPIIYFFVGSFRKQWRLRQPILKLALQRALQDTAEVDHSEGCFSQGTLEMSRSSLV |
UniProt | Q4QXU5 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3831324 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL3719266 |
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Molecular formula | C34H36N8O3 |
IUPAC name | 1-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-N-methyl-2-(3-phenoxyphenyl)-N-(2-pyridin-2-ylethyl)benzimidazole-5-carboxamide |
Molecular weight | 604.715 |
Hydrogen bond acceptor | 6 |
Hydrogen bond donor | 3 |
XlogP | 3.3 |
Synonyms | SCHEMBL14020514 |
Inchi Key | BRYPYUOISATLPO-PMERELPUSA-N |
Inchi ID | InChI=1S/C34H36N8O3/c1-41(20-17-25-10-5-6-18-38-25)33(44)24-15-16-29-28(22-24)40-32(42(29)30(31(35)43)14-8-19-39-34(36)37)23-9-7-13-27(21-23)45-26-11-3-2-4-12-26/h2-7,9-13,15-16,18,21-22,30H,8,14,17,19-20H2,1H3,(H2,35,43)(H4,36,37,39)/t30-/m0/s1 |
PubChem CID | 59819672 |
ChEMBL | CHEMBL3719266 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Efficacy | 18.0 % | None | ChEMBL |
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