You can:
Name | Mas-related G-protein coupled receptor member X1 |
---|---|
Species | Homo sapiens (Human) |
Gene | MRGPRX1 |
Synonym | Sensory neuron-specific G-protein coupled receptor 4 Sensory neuron-specific G-protein coupled receptor 3/4 MRGX1 MRGPRX1 Mrgprc11 [ Show all ] |
Disease | N/A |
Length | 322 |
Amino acid sequence | MDPTISTLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNAFSIYILNLAAADFLFLSGRLIYSLLSFISIPHTISKILYPVMMFSYFAGLSFLSAVSTERCLSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLCGFLFSGADSAWCQTSDFITVAWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQFFLFLWIHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDASEVDEGGGQLPEEILELSGSRLEQ |
UniProt | Q96LB2 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q96LB2 |
3D structure model | This predicted structure model is from GPCR-EXP Q96LB2. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5850 |
IUPHAR | 156 |
DrugBank | N/A |
Name | CHEMBL3719296 |
---|---|
Molecular formula | C30H33N7O4 |
IUPAC name | (2R)-5-(diaminomethylideneamino)-2-[5-(morpholine-4-carbonyl)-2-(3-phenoxyphenyl)benzimidazol-1-yl]pentanamide |
Molecular weight | 555.639 |
Hydrogen bond acceptor | 6 |
Hydrogen bond donor | 3 |
XlogP | 2.0 |
Synonyms | SCHEMBL14020539 |
Inchi Key | HEACHFYTODVTGR-AREMUKBSSA-N |
Inchi ID | InChI=1S/C30H33N7O4/c31-27(38)26(10-5-13-34-30(32)33)37-25-12-11-21(29(39)36-14-16-40-17-15-36)19-24(25)35-28(37)20-6-4-9-23(18-20)41-22-7-2-1-3-8-22/h1-4,6-9,11-12,18-19,26H,5,10,13-17H2,(H2,31,38)(H4,32,33,34)/t26-/m1/s1 |
PubChem CID | 89224504 |
ChEMBL | CHEMBL3719296 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 1584.89 nM | None | ChEMBL |
Efficacy | 203.0 % | None | ChEMBL |
zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218