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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Olfactory receptor 5K1
Species	Homo sapiens (Human)
Gene	OR5K1
Synonym	HTPCRX10 Olfactory receptor OR3-8
Disease	N/A
Length	308
Amino acid sequence	MAEENHTMKNEFILTGFTDHPELKTLLFVVFFAIYLITVVGNISLVALIFTHRRLHTPMYIFLGNLALVDSCCACAITPKMLENFFSENKRISLYECAVQFYFLCTVETADCFLLAAMAYDRYVAICNPLQYHIMMSKKLCIQMTTGAFIAGNLHSMIHVGLVFRLVFCGSNHINHFYCDILPLYRLSCVDPYINELVLFIFSGSVQVFTIGSVLISYLYILLTIFKMKSKEGRAKAFSTCASHFLSVSLFYGSLFFMYVRPNLLEEGDKDIPAAILFTIVVPLLNPFIYSLRNREVISVLRKILMKK
UniProt	Q8NHB7
Protein Data Bank	N/A
GPCR-HGmod model	Q8NHB7
3D structure model	This predicted structure model is from GPCR-EXP Q8NHB7.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3721312
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	Amylcinnamaldehyde
Molecular formula	C14H18O
IUPAC name	(2E)-2-benzylideneheptanal
Molecular weight	202.297
Hydrogen bond acceptor	1
Hydrogen bond donor	0
XlogP	4.2
Synonyms	HMKKIXGYKWDQSV-SDNWHVSQSA-N RTR-003591 WLN: VHY5 & U1R .alpha.-Amyl-.beta.-phenylacrolein 2-Propenal, 3-phenyl-, monopentyl deriv. alpha-Amylcinnamaldehyde alpha-Amylcinnamaldehyde, mixture of cis and trans, >=97%, stabilized, FG CHEMBL1989481 L943 ST24027781 .alpha.-Amylcinnamicaldehyde a-amylcinnamaldehyde alpha-n-Amylcinnamaldehyde Heptanal, 2-(phenylmethylene)- NSC6649 UNII-WC51CA3418 component HMKKIXGYKWDQSV-SDNWHVSQSA-N (2E)-2-benzylideneheptanal 1331-92-6 AKOS030505815 alpha-Amylcinnamaldehyde, 97%, mixture of cis and trans CC-23944 Jsp001501 SC-19015 ZINC4764408 .alpha.-Amylcinnamaldehyde 78605-96-6 alpha-Amylcinnamaldehyde, mixture of cis and trans, analytical standard CJ-12273 MolPort-001-783-107 TR-003591 .alpha.-Pentylcinnamaldehyde AC1LV1G2 alpha-Pentylcinnamaldehyde Heptanal, 2-(phenylmethylene)-, (2E)- RP17493 W-108431 (E)-2-benzylideneheptanal 2-Pentyl-3-phenylpropenoic al alpha-amylcinnamal alpha-Amylcinnamaldehyde, mixture of cis and trans, >=97%, natural, FG KB-47273 SCHEMBL113319 .alpha.-Amylcinnamic aldehyde 86L63D4ZJ7 alpha-Amylcinnamic aldehyde EC 800-696-3 NSC-6649 UNII-86L63D4ZJ7 (2E)-2-(phenylmethylidene)heptanal 122-40-7 AC1Q2VC4 [ Show all ]
Inchi Key	HMKKIXGYKWDQSV-SDNWHVSQSA-N
Inchi ID	InChI=1S/C14H18O/c1-2-3-5-10-14(12-15)11-13-8-6-4-7-9-13/h4,6-9,11-12H,2-3,5,10H2,1H3/b14-11+
PubChem CID	1623625
ChEMBL	CHEMBL1989481
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	75.0 %	None	ChEMBL

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